Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6059
Gene Symbol: ABCE1
ABCE1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.100 AlteredExpression BEFREE The expression levels of Tip60 and ABCE1 acetylation were examined using western blot and co-immunoprecipitation (Co-IP) assays in normal bronchial epithelial (HBE) and human lung cancer (A549) cells. 30936993

2019
Entrez Id: 6059
Gene Symbol: ABCE1
ABCE1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.100 AlteredExpression BEFREE Moreover, the impairment of RNase L in lung cancer cells was due to the elevated expression of RLI. 31501431

2019
Entrez Id: 6059
Gene Symbol: ABCE1
ABCE1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.100 AlteredExpression BEFREE MiR-153 inhibits the resistance of lung cancer to gefitinib via modulating expression of ABCE1. 31306106

2019
Entrez Id: 6059
Gene Symbol: ABCE1
ABCE1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.100 Biomarker BEFREE These findings indicate that ABCE1 is involved in the development and progression of lung cancer through the CCL7 signaling pathway. 30214518

2018
Entrez Id: 6059
Gene Symbol: ABCE1
ABCE1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.100 Biomarker BEFREE The Fe-S clusters of ABCE1 may be potential targets for the prevention of lung cancer metastasis. 29145194

2017
Entrez Id: 6059
Gene Symbol: ABCE1
ABCE1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.100 Biomarker BEFREE We have previously shown that ABCE1 is a prognostic indicator for lung cancer, although the underlying mechanisms remain unclear. 26733164

2016
Entrez Id: 6059
Gene Symbol: ABCE1
ABCE1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.100 AlteredExpression BEFREE Taken together, these data suggest that overexpression of ABCE1 produces an obvious effect on the motility of lung cancer cells through cytoskeleton rearrangement. 27109616

2016
Entrez Id: 6059
Gene Symbol: ABCE1
ABCE1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.100 Biomarker BEFREE In conclusion, the present study suggested that ABCE1 promotes the growth, invasion and metastasis of lung adenocarcinoma cells and may represent a potential biomarker and therapeutic target for lung cancer. 27314749

2016
Entrez Id: 6059
Gene Symbol: ABCE1
ABCE1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.100 Biomarker BEFREE Therefore, the disordered decreased of miR-299-3p and resulting ABCE1 up-expression may contribute to chemoresistance of lung cancer, and miR-299-3p-ABCE1 may represent a new potential therapeutic target for the treatment of chemoresistance of lung cancer. 26617714

2015
Entrez Id: 6059
Gene Symbol: ABCE1
ABCE1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.100 Biomarker BEFREE This work aimed to investigate the alterations in chemosensitivity of A549 lung cancer cells for 5-Fluorouracil (5-FU) and irinotecan by silencing ABCE1 using specific small interfering RNAs (siRNA). 25744244

2015
Entrez Id: 6059
Gene Symbol: ABCE1
ABCE1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.100 AlteredExpression BEFREE Studies in lung cancer have shown that overexpression of ABCE1 in tumor cells promotes growth and inhibits apoptosis. 25070080

2014