Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
CUI: C1456781
Disease: Benign melanocytic nevus
Benign melanocytic nevus 		0.050 AlteredExpression BEFREE Seven of 11 cases showed loss of nuclear BAP1 immunohistochemical (IHC) expression in the malignant component, sparing the adjacent nevus. 26645730

2016
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
CUI: C1456781
Disease: Benign melanocytic nevus
Benign melanocytic nevus 		0.050 AlteredExpression BEFREE We investigated BAP1 and BRAFV600E expression in 193 sporadic melanocytic lesions (11 dermal nevi, 20 congenital nevi, 40 primary and nondesmoplastic melanomas, 40 desmoplastic melanomas, 23 metastatic melanomas, 17 Spitz nevi, 19 atypical Spitz nevi, 8 atypical Spitz tumors, 14 proliferative nodules arising in congenital nevi, 1 nevus during pregnancy) and 30 melanocytic lesions from 3 patients with family history of uveal melanoma and BAP1 germline mutation. 25479927

2015
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
CUI: C1456781
Disease: Benign melanocytic nevus
Benign melanocytic nevus 		0.050 Biomarker BEFREE Adipocytic metaplasia and nuclear pseudoinclusions may be additional morphologic clues to a BAP1-deficient nevus. 25902915

2015
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
CUI: C1456781
Disease: Benign melanocytic nevus
Benign melanocytic nevus 		0.050 Biomarker BEFREE We present an unusual case of sporadic Wiesner nevus that had typical histopathologic features and a BAP1 but not a BRAF mutation. 25953246

2015
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
CUI: C1456781
Disease: Benign melanocytic nevus
Benign melanocytic nevus 		0.050 AlteredExpression BEFREE We describe a 21-year-old patient with multiple combined melanocytic proliferations composed of both a nevus component with strong BAP1 expression and a large epithelioid melanocyte population with loss of BAP1 expression. 23552620

2013