DisGeNET - a database of gene-disease associations

Source: BEFREE

Disease: Diabetic foot ulcer ×

Gene: CXCL12 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	6387
Gene Symbol:	CXCL12

CXCL12

CUI:	C1456868
Disease:	Diabetic foot ulcer

Diabetic foot ulcer

0.030

Biomarker

BEFREE

miR-23c regulates wound healing by targeting stromal cell-derived factor-1α (SDF-1α/CXCL12) among patients with diabetic foot ulcer.

31520606

2020

Entrez Id:	6387
Gene Symbol:	CXCL12

CXCL12

CUI:	C1456868
Disease:	Diabetic foot ulcer

Diabetic foot ulcer

0.030

AlteredExpression

BEFREE

Subjects with DFU (n = 270) were genotyped by PCR-RFLP and the serum levels of IL-6, TNF-α and SDF-1 were determined by ELISA.

30009916

2018

Entrez Id:	6387
Gene Symbol:	CXCL12

CXCL12

CUI:	C1456868
Disease:	Diabetic foot ulcer

Diabetic foot ulcer

0.030

AlteredExpression

BEFREE

Genetic association of IL-6, TNF-α and SDF-1 polymorphisms with serum cytokine levels in diabetic foot ulcer.

25839939

2015