Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C1619700
Disease: RENAL ADYSPLASIA
RENAL ADYSPLASIA 		0.440 GeneticVariation BEFREE Although it is well known that RET mutation causes multiple endocrine neoplasia type 2A (MEN2A), thus far only 3 individuals have been reported to have MEN2A and renal agenesis/dysgenesis. 24152999

2014
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C1619700
Disease: RENAL ADYSPLASIA
RENAL ADYSPLASIA 		0.440 GeneticVariation BEFREE These results suggest that genomic alteration of RET or GDNF is not a major mechanism leading to renal agenesis and other severe kidney development defects. 21490379

2011
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C1619700
Disease: RENAL ADYSPLASIA
RENAL ADYSPLASIA 		0.440 GeneticVariation BEFREE Renal aplasia in humans is associated with RET mutations. 18252215

2008
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C1619700
Disease: RENAL ADYSPLASIA
RENAL ADYSPLASIA 		0.440 GeneticVariation BEFREE A targeted mutation in the tyrosine kinase domain of RET produced total intestinal aganglionosis and renal agenesis in homozygous transgenic mice. 11316186

2001