Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2160
Gene Symbol: F11
F11
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.140 Biomarker BEFREE FXIa (factor XIa) induces clot formation, and human congenital FXI deficiency protects against venous thromboembolism and stroke. 31766871

2020
Entrez Id: 2160
Gene Symbol: F11
F11
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.140 Biomarker BEFREE SUMMARY: Background and objectives Low factor XI activity (FXIa) reduces the risk of venous thromboembolism (VTE), and FXI is regarded as a potential target for anticoagulation. 30784172

2019
Entrez Id: 2160
Gene Symbol: F11
F11
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.140 GeneticVariation BEFREE We studied prospectively the associations of plasma factor XI and a key F11 genetic variant with incident VTE in whites and African-Americans. 26260105

2015
Entrez Id: 2160
Gene Symbol: F11
F11
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism 		0.140 GeneticVariation BEFREE A nucleotide variant (rs3756008) in the promoter region of the FXI gene was recently reported for association with venous thromboembolism. 24420855

2014