Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7706
Gene Symbol: TRIM25
TRIM25
CUI: C2062441
Disease: Influenza A
Influenza A 		0.050 Biomarker BEFREE Despite this, loss of TRIM25 results in greater susceptibility to IAV infection in vivo, suggesting that it may have an alternative role in host antiviral defense. 31335993

2019
Entrez Id: 7706
Gene Symbol: TRIM25
TRIM25
CUI: C2062441
Disease: Influenza A
Influenza A 		0.050 AlteredExpression BEFREE TRIM25 activity is targeted by influenza A virus non-structural protein 1 (NS1) to suppress IFN production and prevent an efficient host immune response. 29739942

2018
Entrez Id: 7706
Gene Symbol: TRIM25
TRIM25
CUI: C2062441
Disease: Influenza A
Influenza A 		0.050 Biomarker BEFREE Here we present a nuclear role for TRIM25 in specifically restricting influenza A virus replication. 29107643

2017
Entrez Id: 7706
Gene Symbol: TRIM25
TRIM25
CUI: C2062441
Disease: Influenza A
Influenza A 		0.050 AlteredExpression BEFREE It is known that the influenza A virus NS1 protein (NS1-A) interacts with RIG-I and TRIM25 to suppress the activation of RIG-I-mediated signaling. 27122586

2016
Entrez Id: 7706
Gene Symbol: TRIM25
TRIM25
CUI: C2062441
Disease: Influenza A
Influenza A 		0.050 Biomarker BEFREE Here, we report that the influenza A virus nonstructural protein 1 (NS1) specifically inhibits TRIM25-mediated RIG-I CARD ubiquitination, thereby suppressing RIG-I signal transduction. 19454348

2009