Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C2145472
Disease: Urothelial Carcinoma
Urothelial Carcinoma 		0.090 AlteredExpression BEFREE Prognostic significance of epidermal growth factor receptor (EGFR) over expression in urothelial carcinoma of urinary bladder. 29879970

2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C2145472
Disease: Urothelial Carcinoma
Urothelial Carcinoma 		0.090 AlteredExpression BEFREE HER2 and EGFR amplification and expression in urothelial carcinoma occurs in distinct biological and molecular contexts. 28388586

2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C2145472
Disease: Urothelial Carcinoma
Urothelial Carcinoma 		0.090 GeneticVariation BEFREE We studied whether afatinib (an oral, irreversible inhibitor of the ErbB family) has activity in UC and if specific ERBB molecular alterations are associated with clinical response. 27044931

2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C2145472
Disease: Urothelial Carcinoma
Urothelial Carcinoma 		0.090 Biomarker BEFREE Afatinib Is Active in Platinum-Refractory ERBB-Mutant Urothelial Carcinoma. 27080337

2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C2145472
Disease: Urothelial Carcinoma
Urothelial Carcinoma 		0.090 AlteredExpression BEFREE AR activation up-regulates EGFR and HER2/neu expression contributing to UC progression. 26044568

2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C2145472
Disease: Urothelial Carcinoma
Urothelial Carcinoma 		0.090 Biomarker BEFREE SH3BGRL3 Protein as a Potential Prognostic Biomarker for Urothelial Carcinoma: A Novel Binding Partner of Epidermal Growth Factor Receptor. 26286913

2015
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C2145472
Disease: Urothelial Carcinoma
Urothelial Carcinoma 		0.090 Biomarker BEFREE Most importantly, E-cadherin seems to play a central role in modulation of EGFR response in urothelial carcinoma. 18316572

2008
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C2145472
Disease: Urothelial Carcinoma
Urothelial Carcinoma 		0.090 GeneticVariation BEFREE Therefore, it is important to determine if these EGFR alterations are present in urothelial carcinoma. 17690890

2007
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C2145472
Disease: Urothelial Carcinoma
Urothelial Carcinoma 		0.090 Biomarker BEFREE The focus of this study was to determine if these alterations are present within the tyrosine kinase and ligand-binding domain of EGFR in urothelial carcinoma. 16899617

2006