Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4525300
Disease: Stage IIA Gallbladder Cancer AJCC v8
Stage IIA Gallbladder Cancer AJCC v8 		0.060 Biomarker BEFREE Consistent with this, treatment with ERBB2-specific, EGFR-specific shRNA or with a covalent EGFR family inhibitor Afatinib inhibits tumor-associated characteristics of the gallbladder cancer cells. 30304546

2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4525300
Disease: Stage IIA Gallbladder Cancer AJCC v8
Stage IIA Gallbladder Cancer AJCC v8 		0.060 GeneticVariation BEFREE We present a 73-year-old female patient who underwent curative resection for GBC harboring epidermal growth factor receptor 2 (ERBB2) activating mutation on next-generation sequencing (NGS)-based genomic testing. 31558980

2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4525300
Disease: Stage IIA Gallbladder Cancer AJCC v8
Stage IIA Gallbladder Cancer AJCC v8 		0.060 Biomarker BEFREE Pharmacological inhibition or inhibition via RNA interference of epidermal growth factor receptor induced cellular senescence in gallbladder cancer cells. 28459363

2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4525300
Disease: Stage IIA Gallbladder Cancer AJCC v8
Stage IIA Gallbladder Cancer AJCC v8 		0.060 AlteredExpression BEFREE This study has been done to see the EGFR expression in GBC in Indian context. 27461681

2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4525300
Disease: Stage IIA Gallbladder Cancer AJCC v8
Stage IIA Gallbladder Cancer AJCC v8 		0.060 AlteredExpression BEFREE In conclusion, the present study indicated that the mechanism of action of miR-146b-5p in GBC involves the regulation of EGFR expression. 25760482

2015
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C4525300
Disease: Stage IIA Gallbladder Cancer AJCC v8
Stage IIA Gallbladder Cancer AJCC v8 		0.060 Biomarker BEFREE There have been no previous reports of chemotherapy plus an EGFR-tyrosine kinase inhibitor (TKI) to treat gallbladder cancer or correlations of response with the mutation status of the tyrosine kinase domain of the EGFR gene. 20961434

2010