Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2
CUI: C4525305
Disease: Stage IV Gallbladder Cancer AJCC v8
Stage IV Gallbladder Cancer AJCC v8 		0.050 Biomarker BEFREE Our study identified that SLC25A22 promoted development of GBC activating MAPK/ERK pathway. 30814911

2019
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2
CUI: C4525305
Disease: Stage IV Gallbladder Cancer AJCC v8
Stage IV Gallbladder Cancer AJCC v8 		0.050 Biomarker BEFREE EMP3, which is regulated by miR-663a, suppresses gallbladder cancer progression via interference with the MAPK/ERK pathway. 29778567

2018
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2
CUI: C4525305
Disease: Stage IV Gallbladder Cancer AJCC v8
Stage IV Gallbladder Cancer AJCC v8 		0.050 Biomarker BEFREE Therefore, ERK1/2 and p-ERK1/2 seem to be important in the development of GBC and GB-d1, G415 and NOZ cell lines may be used as experimental models for further in vitro and in vivo studies that help to decipher the role of MAPK/ERK pathway in gallbladder carcinogenesis. 28285962

2017
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2
CUI: C4525305
Disease: Stage IV Gallbladder Cancer AJCC v8
Stage IV Gallbladder Cancer AJCC v8 		0.050 AlteredExpression BEFREE PHB and p-ERK protein expressions were determined in human GBC tissues by immunohistochemistry (IHC). 27084680

2016
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2
CUI: C4525305
Disease: Stage IV Gallbladder Cancer AJCC v8
Stage IV Gallbladder Cancer AJCC v8 		0.050 AlteredExpression BEFREE ARB blocked A2-induced GBC cell growth and activated ERK. 25663464

2015