Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE YAP1-induced MALAT1 promotes epithelial-mesenchymal transition and angiogenesis by sponging miR-126-5p in colorectal cancer. 30531836

2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE MALAT1 sponges miR-106b-5p to promote the invasion and metastasis of colorectal cancer via SLAIN2 enhanced microtubules mobility. 30797712

2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE Inhibition of MALAT1 reduces tumor growth and metastasis and promotes drug sensitivity in colorectal cancer. 30716387

2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE Multivariate Cox regression analysis showed that MALAT1 was a poor prognostic factor of colorectal cancer. 31311811

2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE Nonetheless, whether Malat1 participates in the autophagy of colorectal cancer remains unclear. 31372165

2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 AlteredExpression BEFREE Collectively, we concluded that MALAT1 functioned as a ceRNA to promote colorectal cancer development and EZH2 expression through sponging miR-363-3p <i>in vitro</i> and <i>in vivo</i>. 30972996

2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 AlteredExpression BEFREE In particular, increased MALAT1 expression levels were significantly associated with decreased OS in patients with colorectal cancer (HR, 3.04; 95% CI, 1.77-4.31). 30719108

2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE The long non-coding RNA MALAT1 promotes epithelial-mesenchymal transition and angiogenesis in colorectal cancer, but it is unknown whether it affects the stemness of gastric cancer cells. 31037832

2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 AlteredExpression BEFREE MALAT1 can be aberrantly expressed in hepatocellular carcinoma, cervical, breast, ovarian cancers, as well as colorectal cancer. 29096355

2018
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 GeneticVariation BEFREE Association study of genetic variation of lncRNA MALAT1 with carcinogenesis of colorectal cancer. 30538572

2018
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE LncRNA MALAT1 could facilitate colorectal cancer cell proliferation, invasion and migration by down-regulating miR-145 and up-regulating SOX9. 30285605

2018
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE MALAT1 promotes the colorectal cancer malignancy by increasing DCP1A expression and miR203 downregulation. 29964337

2018
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE EZH2 is highly expressed and associated with the 3' end region of lncRNA MALAT1 in colorectal cancer, and this association suppressed the expression of E-cadherin. 28069878

2017
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 AlteredExpression BEFREE Recent studies have demonstrated that MALAT1 is involved in cancer metastasis and recurrence and it is up-regulated in cervical cancer, hepatocellular carcinoma, non-small cell lung cancer (NSCLC) and colorectal cancer. 26406400

2015
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 AlteredExpression BEFREE An aberrant expression of MALAT1 was observed in hepatocellular carcinoma, cervical cancer, breast cancer, ovarian cancer, and colorectal cancer. 25431257

2015
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE High expression of lncRNA MALAT1 suggests a biomarker of poor prognosis in colorectal cancer. 25031737

2014
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE MALAT-1: a long non-coding RNA and its important 3' end functional motif in colorectal cancer metastasis. 21503572

2011