Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 AlteredExpression BEFREE We extracted and estimated the hazard ratios for survival outcomes, which compared low and high expression levels of miR-143/145 in colorectal cancer patients in the available studies. 30854930

2019
Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE MicroRNA-143-3p suppresses tumorigenesis by targeting catenin-δ1 in colorectal cancer. 31118676

2019
Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 AlteredExpression BEFREE Expression levels of miR-143-3p and -424-5p in colorectal cancer and their clinical significance. 30883340

2019
Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE MicroRNA-143-3p inhibits colorectal cancer metastases by targeting ITGA6 and ASAP3. 30536996

2019
Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE The novel long intergenic noncoding RNA UCC promotes colorectal cancer progression by sponging miR-143. 28492554

2017
Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE PART-1 functions as a competitive endogenous RNA for promoting tumor progression by sponging miR-143 in colorectal cancer. 28619512

2017
Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE MicroRNA-143 inhibits colorectal cancer cell proliferation by targeting MMP7. 27827523

2017
Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 GeneticVariation BEFREE A functional variant rs353292 in the flanking region of miR-143/145 contributes to the risk of colorectal cancer. 27444415

2016
Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE MicroRNA-143 replenishment re-sensitizes colorectal cancer cells harboring mutant, but not wild-type, KRAS to paclitaxel treatment. 26581910

2016
Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 GeneticVariation BEFREE A polymorphism rs4705341 in the flanking region of miR-143/145 predicts risk and prognosis of colorectal cancer. 27556691

2016
Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE MicroRNA Expression Profile Reveals miR-17-92 and miR-143-145 Cluster in Synchronous Colorectal Cancer. 26266366

2015
Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE MiR-143 and MiR-145 regulate IGF1R to suppress cell proliferation in colorectal cancer. 25474488

2014
Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE These results establish a complex network of regulation through which the miR-143/145 cluster is able to modulate KRAS signaling in colorectal cancer. 22751122

2013
Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 GeneticVariation BEFREE Association between polymorphisms in the promoter region of miR-143/145 and risk of colorectal cancer. 23628392

2013
Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE MicroRNA-143 targets MACC1 to inhibit cell invasion and migration in colorectal cancer. 22533346

2012
Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 GeneticVariation BEFREE We found that 67 miRNA precursors are upregulated in rectal cancer (p<0.05) and 21 of those have never been reported in colorectal cancer (CRC); 39 miRNA precursors are downregulated (p<0.05) and 24 novel dysregulated miRNAs were identified in rectal cancer. miR-31, miR-126 and miR-143 are differentially expressed between colon cancer and rectal cancer. 22576798

2012
Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE The miR-143 showed a significant tumor-suppressive effect on xenografted tumors of DLD-1 human colorectal cancer cells. 20094072

2010
Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer. 19638978

2009
Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.100 Biomarker BEFREE Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer. 18196926

2007