Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 406941
Gene Symbol: MIR149
MIR149
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE Mir-149 rs2292832 may modulate the risk of gastrointestinal tract cancers especially colorectal cancer. 30930933

2019

Entrez Id: 406941
Gene Symbol: MIR149
MIR149
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE LncRNA PCAT-1 regulated cell proliferation, invasion, migration and apoptosis in colorectal cancer through targeting miR-149-5p. 31646561

2019

Entrez Id: 406941
Gene Symbol: MIR149
MIR149
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE circANKS1B regulates FOXM1 expression and promotes cell migration and invasion by functioning as a sponge of the miR-149 in colorectal cancer. 31213828

2019

Entrez Id: 406941
Gene Symbol: MIR149
MIR149
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE MicroRNA-149 sensitizes colorectal cancer to radiotherapy by downregulating human epididymis protein 4. 29416918

2018

Entrez Id: 406941
Gene Symbol: MIR149
MIR149
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE MicroRNA-149 Increases the Sensitivity of Colorectal Cancer Cells to 5-Fluorouracil by Targeting Forkhead Box Transcription Factor FOXM1. 27415661

2016

Entrez Id: 406941
Gene Symbol: MIR149
MIR149
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Associations of Polymorphisms in mir-196a2, mir-146a and mir-149 with Colorectal Cancer Risk: A Meta-Analysis. 26208586

2016

Entrez Id: 406941
Gene Symbol: MIR149
MIR149
Malignant neoplasm of colon and/or rectum
0.100 PosttranslationalModification BEFREE SP1 mediates the link between methylation of the tumour suppressor miR-149 and outcome in colorectal cancer. 22821729

2013

Entrez Id: 406941
Gene Symbol: MIR149
MIR149
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression BEFREE Non-CpG island promoter hypomethylation and miR-149 regulate the expression of SRPX2 in colorectal cancer. 23115050

2013

Entrez Id: 406941
Gene Symbol: MIR149
MIR149
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE Among those that engaged in smoke inhalation, miR-149 CT/CC and miR-605 AG/GG genotype carriers had increased susceptibilities to colorectal cancer (OR = 1.90, 95% CI: 1.11-3.25) and gastric cancer (OR = 1.87, 95% CI: 1.03-3.42), respectively. 21976437

2012

Entrez Id: 406941
Gene Symbol: MIR149
MIR149
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE When stratified by cancer type, there were no significant cancer risk changes for lung cancer, breast cancer or colorectal cancer when miR-149 T allele was included. 22714913

2012