×
Entrez Id: 407018
Gene Symbol: MIR27A
MIR27A
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
The diagnostic sensitivity, specificity and accordance rates of positive miR-27a and miR-31 expression in colorectal cancer were recorded.
31452786 2019
×
Entrez Id: 407018
Gene Symbol: MIR27A
MIR27A
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Patients with colorectal cancer with high expression of circulating exosomal miR-27a or miR-130a underwent poorer prognosis.<b>Conclusions:</b> We identified a circulating exosomal miRNAs panel for the detection of colorectal cancer .<b>Impact:</b> The exosomal miR-27a and miR-130a panel in plasma may act as a noninvasive biomarker for early detection and predicting prognosis of colorectal cancer .
29739748 2018
×
Entrez Id: 407018
Gene Symbol: MIR27A
MIR27A
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
miR-27a -3p targeting RXRα promotes colorectal cancer progression by activating Wnt/β-catenin pathway.29137318 2017
×
Entrez Id: 407018
Gene Symbol: MIR27A
MIR27A
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Knockdown of microRNA-27a resensitized colorectal cancer stem cells to TRAIL-induced cell death.
28423356 2017
×
Entrez Id: 407018
Gene Symbol: MIR27A
MIR27A
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
miR‑27a promotes proliferation, migration, and invasion of colorectal cancer by targeting FAM172A and acts as a diagnostic and prognostic biomarker.28440497 2017
×
Entrez Id: 407018
Gene Symbol: MIR27A
MIR27A
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Association between microRNA-27a rs895819 polymorphism and risk of colorectal cancer : A meta-analysis.
27751356 2016
×
Entrez Id: 407018
Gene Symbol: MIR27A
MIR27A
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Proteomic screening identifies calreticulin as a miR-27a direct target repressing MHC class I cell surface exposure in colorectal cancer .
26913609 2016
×
Entrez Id: 407018
Gene Symbol: MIR27A
MIR27A
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Genotype GG of rs895819 Functional Polymorphism Within miR-27a Might Increase Genetic Susceptibility to Colorectal Cancer in Han Chinese Population.
26302683 2016
×
Entrez Id: 407018
Gene Symbol: MIR27A
MIR27A
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
The overexpression of miR-27a in the human colorectal cancer cell line HCT-116<sup>+/+</sup> resulted in the decreased expression of the endogenous p53 protein levels.
27531966 2016
×
Entrez Id: 407018
Gene Symbol: MIR27A
MIR27A
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Novel Evidence for Curcumin and Boswellic Acid-Induced Chemoprevention through Regulation of miR-34a and miR-27a in Colorectal Cancer .
25712055 2015
×
Entrez Id: 407018
Gene Symbol: MIR27A
MIR27A
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Association between miR-27a genetic variants and susceptibility to colorectal cancer .
25078482 2014
×
Entrez Id: 407018
Gene Symbol: MIR27A
MIR27A
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Association between a functional variant in microRNA-27a and susceptibility to colorectal cancer in a Chinese Han population.
25222241 2014
×
Entrez Id: 407018
Gene Symbol: MIR27A
MIR27A
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Therefore, miR-27a could be a useful biomarker for monitoring colorectal cancer development and progression, and also could have a therapeutic potential by targeting SGPP1, Smad2 and STAT3 for colorectal cancer therapy.
25166914 2014
×
Entrez Id: 407018
Gene Symbol: MIR27A
MIR27A
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Evaluation of SNPs in miR-196-a2, miR-27a and miR-146a as risk factors of colorectal cancer .
22719192 2012
×
Entrez Id: 407018
Gene Symbol: MIR27A
MIR27A
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
The FCS method had a significant advantage over miRNA differential expression analysis when identifying cancer-related miRNAs with a fine regulatory mechanism, such as miR-27a in colorectal cancer .
21976726 2011