Source: CLINVAR

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 238
Gene Symbol: ALK
ALK
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.610 GeneticVariation CLINVAR Differential inhibitor sensitivity of anaplastic lymphoma kinase variants found in neuroblastoma. 22072639

2011
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.500 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.500 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.500 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.500 GeneticVariation CLINVAR Combined PTEN Mutation and Protein Expression Associate with Overall and Disease-Free Survival of Glioblastoma Patients. 24721394

2014
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.500 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.500 GeneticVariation CLINVAR An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. 23558169

2013
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.500 GeneticVariation CLINVAR Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy. 22586120

2012
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.500 GeneticVariation CLINVAR Targeted therapy for BRAFV600E malignant astrocytoma. 22038996

2011
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.500 GeneticVariation CLINVAR Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain. 17177598

2006
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.500 GeneticVariation CLINVAR PTEN controls tumor-induced angiogenesis. 11274365

2001
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.480 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.200 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.200 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.130 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 3020
Gene Symbol: H3-3A
H3-3A
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.130 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.100 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.100 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016