Source: CLINVAR

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.200 GeneticVariation CLINVAR The strong dimerization of the transmembrane domain of the fibroblast growth factor receptor (FGFR) is modulated by C-terminal juxtamembrane residues. 19165726

2009
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.200 GeneticVariation CLINVAR Constitutive activating mutation of the FGFR3b in oral squamous cell carcinomas. 15880580

2005
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.200 GeneticVariation CLINVAR Differential activation of cysteine-substitution mutants of fibroblast growth factor receptor 3 is determined by cysteine localization. 12009017

2002
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.200 GeneticVariation CLINVAR Deregulated FGFR3 mutants in multiple myeloma cell lines with t(4;14): comparative analysis of Y373C, K650E and the novel G384D mutations. 11429702

2001
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.200 GeneticVariation CLINVAR Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas. 10471491

1999
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.200 GeneticVariation CLINVAR Effect of transmembrane and kinase domain mutations on fibroblast growth factor receptor 3 chimera signaling in PC12 cells. A model for the control of receptor tyrosine kinase activation. 9857065

1998