DisGeNET - a database of gene-disease associations

Source: CLINVAR

Disease: Neoplasms ×

Gene: TP53 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	7157
Gene Symbol:	TP53

TP53

CUI:	C0027651
Disease:	Neoplasms

Neoplasms

0.200

GeneticVariation

CLINVAR

Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

25157968

2014

Entrez Id:	7157
Gene Symbol:	TP53

TP53

CUI:	C0027651
Disease:	Neoplasms

Neoplasms

0.200

GeneticVariation

CLINVAR

Mutant p53 in cancer: new functions and therapeutic opportunities.

24651012

2014

Entrez Id:	7157
Gene Symbol:	TP53

TP53

CUI:	C0027651
Disease:	Neoplasms

Neoplasms

0.200

GeneticVariation

CLINVAR

p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation.

18391940

2008

Entrez Id:	7157
Gene Symbol:	TP53

TP53

CUI:	C0027651
Disease:	Neoplasms

Neoplasms

0.200

GeneticVariation

CLINVAR

Structural basis for understanding oncogenic p53 mutations and designing rescue drugs.

17015838

2006

Entrez Id:	7157
Gene Symbol:	TP53

TP53

CUI:	C0027651
Disease:	Neoplasms

Neoplasms

0.200

GeneticVariation

CLINVAR

Role of the p53-homologue p73 in E2F1-induced apoptosis.

11101847

2000