×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
Identification of De Novo DNMT3A Mutations That Cause West Syndrome by Using Whole-Exome Sequencing.
28386848
2018
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
Exome sequencing reveals DNMT3A and ASXL1 variants associate with progression of chronic myeloid leukemia after tyrosine kinase inhibitor therapy.
28667884
2017
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
The spectrum of DNMT3A variants in Tatton-Brown-Rahman syndrome overlaps with that in hematologic malignancies.
28941052
2017
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
Novel DNMT3A germline mutations are associated with inherited Tatton-Brown-Rahman syndrome.
27701732
2017
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
Acute myeloid leukemia-associated DNMT3A p.Arg882His mutation in a patient with Tatton-Brown-Rahman overgrowth syndrome as a constitutional mutation.
27991732
2017
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
Mutations in Epigenetic Regulation Genes Are a Major Cause of Overgrowth with Intellectual Disability.
28475857
2017
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
Tatton-Brown-Rahman syndrome due to 2p23 microdeletion.
26866722
2016
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
Mutations in the DNA methyltransferase gene DNMT3A cause an overgrowth syndrome with intellectual disability.
24614070
2014
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
Detection of clinically relevant genetic variants in autism spectrum disorder by whole-genome sequencing.
23849776
2013
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
De novo mutations revealed by whole-exome sequencing are strongly associated with autism.
22495306
2012
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
The DNMT3 family of mammalian de novo DNA methyltransferases.
21507354
2011
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
An evidence-based approach to establish the functional and clinical significance of copy number variants in intellectual and developmental disabilities.
21844811
2011
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
DNMT3A mutations in acute myeloid leukemia.
21067377
2010
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons.
20228804
2010
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens.
20729844
2010
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes.
20651149
2010
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
The NCBI BioSystems database.
19854944
2010
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
DECIPHER: Database of Chromosomal Imbalance and Phenotype in Humans Using Ensembl Resources.
19344873
2009
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons.
17878930
2007
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
Coordinate regulation of DNA methyltransferase expression during oogenesis.
17445268
2007
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
Roles for Dnmt3b in mammalian development: a mouse model for the ICF syndrome.
16501171
2006
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
The Polycomb group protein EZH2 directly controls DNA methylation.
16357870
2006
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
Dynamic expression of DNMT3a and DNMT3b isoforms during male germ cell development in the mouse.
16725135
2006
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system.
15672446
2005
×
Entrez Id:
1788
Gene Symbol:
DNMT3A
DNMT3A
Dysmorphic features
0.100
CausalMutation
CLINVAR
DNA methyltransferase expression in the mouse germ line during periods of de novo methylation.
15739230
2005