×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
Large scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants: An ENIGMA resource to support clinical variant classification.
31131967
2019
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations.
29446198
2018
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
Full in-frame exon 3 skipping of BRCA2 confers high risk of breast and/or ovarian cancer.
29707112
2018
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
Current guidelines for BRCA testing of breast cancer patients are insufficient to detect all mutation carriers.
28637432
2017
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
BRCA1/2 missense mutations and the value of in-silico analyses.
28807866
2017
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
Assessing the spectrum of germline variation in Fanconi anemia genes among patients with head and neck carcinoma before age 50.
28678401
2017
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
Identification of a Novel BRCA1 Pathogenic Mutation in Korean Patients Following Reclassification of BRCA1 and BRCA2 Variants According to the ACMG Standards and Guidelines Using Relevant Ethnic Controls.
28111427
2017
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
GeneticVariation
CLINVAR
Functional classification of DNA variants by hybrid minigenes: Identification of 30 spliceogenic variants of BRCA2 exons 17 and 18.
28339459
2017
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
GeneticVariation
CLINVAR
BRCA1 and BRCA2 mutations in ovarian cancer patients from China: ethnic-related mutations in BRCA1 associated with an increased risk of ovarian cancer.
28176296
2017
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
GeneticVariation
CLINVAR
The spectrum of BRCA mutations and characteristics of BRCA-associated breast cancers in China: Screening of 2,991 patients and 1,043 controls by next-generation sequencing.
28294317
2017
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
Functional classification of DNA variants by hybrid minigenes: Identification of 30 spliceogenic variants of BRCA2 exons 17 and 18.
28339459
2017
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
Prevalence of pathogenic germline variants detected by multigene sequencing in unselected Japanese patients with ovarian cancer.
29348823
2017
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
Male breast cancer in a multi-gene panel testing cohort: insights and unexpected results.
28008555
2017
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
Characteristics of BRCA1/2 mutations carriers including large genomic rearrangements in high risk breast cancer patients.
28205045
2017
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
Recurrent mutations of BRCA1, BRCA2 and PALB2 in the population of breast and ovarian cancer patients in Southern Poland.
26843898
2016
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
Prevalence of BRCA1/BRCA2 mutations in a Brazilian population sample at-risk for hereditary breast cancer and characterization of its genetic ancestry.
27741520
2016
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
Prospective phase II trial of trabectedin in BRCA-mutated and/or BRCAness phenotype recurrent ovarian cancer patients: the MITO 15 trial.
26681678
2016
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
26681312
2016
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
RBP-Var: a database of functional variants involved in regulation mediated by RNA-binding proteins.
26635394
2016
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
Multilocus Inherited Neoplasia Alleles Syndrome: A Case Series and Review.
26659639
2016
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
BRCA-associated pancreatico-biliary neoplasms: Four cases illustrating the emerging clinical impact of genotyping.
26004055
2016
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
GeneticVariation
CLINVAR
BRCA-associated pancreatico-biliary neoplasms: Four cases illustrating the emerging clinical impact of genotyping.
26004055
2016
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer.
26824983
2016
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
CausalMutation
CLINVAR
Mutation detection rates associated with specific selection criteria for BRCA1/2 testing in 1854 high-risk families: A monocentric Italian study.
27062684
2016
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 2
0.700
GeneticVariation
CLINVAR
Adding In Silico Assessment of Potential Splice Aberration to the Integrated Evaluation of BRCA Gene Unclassified Variants.
26913838
2016