×
Entrez Id: 1636
Gene Symbol: ACE
ACE
Alzheimer's Disease
0.900
Biomarker
CTD_human
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
30820047 2019
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
High performance plasma amyloid-β biomarkers for Alzheimer's disease.
29420472 2018
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer's Disease Cerebrospinal Fluid Biomarkers.
30320580 2018
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
Oral administration of methysticin improves cognitive deficits in a mouse model of Alzheimer's disease.
28448946 2017
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's Disease.
27117003 2016
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
This study was designed to explore the protective effect of NTR1 on an APP /PS1 double-transgenic mouse model of AD and investigate the possible mechanism.
25714973 2015
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
Identification of the key molecules involved in chronic copper exposure-aggravated memory impairment in transgenic mice of Alzheimer's disease using proteomic analysis.
25352456 2015
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
Inhibition of human high-affinity copper importer Ctr1 orthologous in the nervous system of Drosophila ameliorates Aβ42-induced Alzheimer's disease-like symptoms.
23827522 2013
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
APP/PS1 transgenic mice treated with aluminum: an update of Alzheimer's disease model.
22507317 2012
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
Increasing the predictive accuracy of amyloid-β blood-borne biomarkers in Alzheimer's disease.
21157020 2011
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
pH-Dependent Cu(II) coordination to amyloid-β peptide: impact of sequence alterations, including the H6R and D7N familial mutations.
21980910 2011
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
Aβ40 oligomers identified as a potential biomarker for the diagnosis of Alzheimer's disease.
21209907 2010
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
On the metal ion (Zn(2+), Cu(2+)) coordination with beta-amyloid peptide: DFT computational study.
20640797 2010
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
Leptin reduces the accumulation of Abeta and phosphorylated tau induced by 27-hydroxycholesterol in rabbit organotypic slices.
20157255 2010
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
Amyloid beta peptide (Abeta), generated by proteolytic cleavage of the amyloid precursor protein (APP ), plays a pivotal role in the pathogenesis of Alzheimer's disease (AD ).
20111991 2010
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis.
19286555 2009
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
APP expression, distribution and accumulation are altered by aluminum in a rodent model for Alzheimer's disease .19818510 2009
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
Here we first reported the differential effects of AD -related metal ions at subtoxic concentrations on the transcription levels of APP and BACE1 in PC12 cells.
18583042 2008
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
Abeta peptides as one of the crucial volume transmission signals in the trophic units and their interactions with homocysteine. Physiological implications and relevance for Alzheimer's disease.
16969627 2007
×
Entrez Id: 1636
Gene Symbol: ACE
ACE
Alzheimer's Disease
0.900
Biomarker
CTD_human
Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database.
17192785 2007
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
Amyloid beta peptide (Abeta), generated by proteolytic cleavage of the amyloid precursor protein (APP ), is central to AD pathogenesis.
17239395 2007
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
"How and when environmental agents and dietary factors affect the course of Alzheimer's disease: the ""LEARn"" model (latent early-life associated regulation) may explain the triggering of AD."
17430250 2007
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
Synchrotron-based infrared and X-ray imaging shows focalized accumulation of Cu and Zn co-localized with beta-amyloid deposits in Alzheimer's disease.
16325427 2006
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
Amyloid-beta peptide binds with heme to form a peroxidase: relationship to the cytopathologies of Alzheimer's disease.
16492752 2006
×
Entrez Id: 351
Gene Symbol: APP
APP
Alzheimer's Disease
0.900
Biomarker
CTD_human
Beta-amyloid mediated nitration of manganese superoxide dismutase: implication for oxidative stress in a APPNLH/NLH X PS-1P264L/P264L double knock-in mouse model of Alzheimer's disease.
16651627 2006