Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2913
Gene Symbol: GRM3
GRM3
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.350 Biomarker PSYGENET Clinical studies have revealed that genetic variations in metabotropic glutamate receptor 3 (mGlu3) affect performance on cognitive tasks dependent upon the prefrontal cortex (PFC) and may be linked to psychiatric conditions such as schizophrenia, bipolar disorder, and addiction. 25583490

2015
Entrez Id: 2913
Gene Symbol: GRM3
GRM3
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.350 Biomarker PSYGENET Identification of base pair changes in the GRM3 gene that affected expression or function of the GRM3 receptor that also showed an allelic association with bipolar disorder. 23575746

2013
Entrez Id: 2913
Gene Symbol: GRM3
GRM3
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.350 Biomarker PSYGENET There is evidence of associations between single nucleotide polymorphisms (SNPs) in GRM3, GRIN2B, and DAOA genes and the diagnosis of BD. 20957330

2010
Entrez Id: 2913
Gene Symbol: GRM3
GRM3
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.350 Biomarker PSYGENET The genes most consistently associated with BD in the genetic studies we reviewed were GSK3beta , GRK3, 5-HTTLPR, GRIN3, COMT, and GLUR3. 20226637

2010
Entrez Id: 2913
Gene Symbol: GRM3
GRM3
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.350 Biomarker PSYGENET However, we did not find any association between GRM3 and BP or the fluvoxamine therapeutic response in MDD in the allele/genotype-wise analysis. 19386277

2009