Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0015967
Disease: Fever
Fever 		0.600 Biomarker CTD_human Deletion of prostaglandin E2 synthesizing enzymes in brain endothelial cells attenuates inflammatory fever. 25164664

2014
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0015967
Disease: Fever
Fever 		0.600 Biomarker CTD_human Mice lacking the Tak1 gene in brain endothelial cells showed a blunted fever response and reduced lethargy upon intravenous injection of the endogenous pyrogen IL-1β. 22143887

2011
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0015967
Disease: Fever
Fever 		0.600 Biomarker CTD_human The role of circulating immune complexes and biocompatibility of staphylococcal protein A immunoadsorption in mitomycin C-induced hemolytic uremic syndrome. 15384034

2004
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0015967
Disease: Fever
Fever 		0.600 Biomarker CTD_human A comparative study of the antipyretic effects of indomethacin and dipyrone in rats. 11852909

2002
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0015967
Disease: Fever
Fever 		0.600 Biomarker CTD_human However, pretreatment with either the IL-1 receptor antagonist or the cyclooxygenase inhibitor flurbiprofen completely abolishes adenovirus-induced fever, suggesting that IL-1 and prostaglandins are direct mediators of this response. 9952427

1999