×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Malignant neoplasm of pancreas
0.800
Biomarker
CTD_human
Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer.
26098869
2015
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Malignant neoplasm of pancreas
0.800
Biomarker
CTD_human
Complete remission, in BRCA2 mutation carrier with metastatic pancreatic adenocarcinoma, treated with cisplatin based therapy.
21613821
2011
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
Malignant neoplasm of pancreas
0.800
Biomarker
CTD_human
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
Malignant neoplasm of pancreas
0.800
CausalMutation
CGI
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Malignant neoplasm of pancreas
0.800
CausalMutation
CGI
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Malignant neoplasm of pancreas
0.800
GenomicAlterations
CGI
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Malignant neoplasm of pancreas
0.800
GeneticVariation
UNIPROT
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Malignant neoplasm of pancreas
0.600
Biomarker
CTD_human
The BET bromodomain inhibitor JQ1 suppresses growth of pancreatic ductal adenocarcinoma in patient-derived xenograft models.
25961927
2016
×
Entrez Id:
6794
Gene Symbol:
STK11
STK11
Malignant neoplasm of pancreas
0.600
Biomarker
CTD_human
Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer.
26098869
2015
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Malignant neoplasm of pancreas
0.600
Biomarker
CTD_human
Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer.
26098869
2015
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of pancreas
0.600
Biomarker
CTD_human
Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer.
26098869
2015
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Malignant neoplasm of pancreas
0.600
Biomarker
CTD_human
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.
26390243
2015
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Malignant neoplasm of pancreas
0.600
Biomarker
CTD_human
Embelin suppresses growth of human pancreatic cancer xenografts, and pancreatic cancer cells isolated from KrasG12D mice by inhibiting Akt and Sonic hedgehog pathways.
24694877
2014
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Malignant neoplasm of pancreas
0.600
Biomarker
CTD_human
Deletion of Rb accelerates pancreatic carcinogenesis by oncogenic Kras and impairs senescence in premalignant lesions.
21699781
2011
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Malignant neoplasm of pancreas
0.600
Biomarker
CTD_human
In this study, we demonstrate that K-Ras , a frequently altered oncogene in human cancers including pancreatic cancer (about 80%), colon cancer (45%) and lung cancer (45%), suppresses p53.
19424582
2009
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Malignant neoplasm of pancreas
0.600
Biomarker
CTD_human
Results lend moderate support to the hypothesis of indirect relationships between occupational exposure to dyes and organic pigments and the activation of the K-ras gene in the etiopathogenesis of human exocrine pancreatic cancer .
14520703
2003
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Malignant neoplasm of pancreas
0.600
Biomarker
CTD_human
Novel germline p16(INK4) allele (Asp145Cys) in a family with multiple pancreatic carcinomas. Mutations in brief no. 148. Online.
10627132
1998
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Malignant neoplasm of pancreas
0.600
GenomicAlterations
CGI
×
Entrez Id:
4089
Gene Symbol:
SMAD4
SMAD4
Malignant neoplasm of pancreas
0.600
GenomicAlterations
CGI
×
Entrez Id:
4089
Gene Symbol:
SMAD4
SMAD4
Malignant neoplasm of pancreas
0.600
CausalMutation
CGI
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Malignant neoplasm of pancreas
0.600
CausalMutation
CGI
×
Entrez Id:
1029
Gene Symbol:
CDKN2A
CDKN2A
Malignant neoplasm of pancreas
0.600
CausalMutation
CGI
×
Entrez Id:
6794
Gene Symbol:
STK11
STK11
Malignant neoplasm of pancreas
0.600
CausalMutation
CGI
×
Entrez Id:
4089
Gene Symbol:
SMAD4
SMAD4
Malignant neoplasm of pancreas
0.600
Biomarker
CTD_human
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Malignant neoplasm of pancreas
0.600
CausalMutation
CGI