Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9582
Gene Symbol: APOBEC3B
APOBEC3B
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.400 Biomarker CTD_human In vitro, APOBEC3B expression was predominantly induced by treatment with a DNA-damaging drug in bladder cancer cell lines, and APOBEC3A expression was induced as part of the antiviral interferon-stimulated response in breast cancer cell lines. 27643540

2016
Entrez Id: 9582
Gene Symbol: APOBEC3B
APOBEC3B
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.400 Biomarker CTD_human A germline copy number polymorphism involving APOBEC3A and APOBEC3B, which effectively deletes APOBEC3B, has been associated with modestly increased risk of breast cancer. 24728294

2014
Entrez Id: 9582
Gene Symbol: APOBEC3B
APOBEC3B
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.400 Biomarker CTD_human We recently showed that the DNA cytidine deaminase APOBEC3B accounts for up to half of the mutational load in breast carcinomas expressing this enzyme. 23852168

2013
Entrez Id: 9582
Gene Symbol: APOBEC3B
APOBEC3B
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.400 Biomarker CTD_human Endogenous APOBEC3B protein is predominantly nuclear and the only detectable source of DNA C-to-U editing activity in breast cancer cell-line extracts. 23389445

2013