Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10008
Gene Symbol: KCNE3
KCNE3
CUI: C1142166
Disease: Brugada Syndrome (disorder)
Brugada Syndrome (disorder) 		0.510 Biomarker CLINGEN Forty consecutive patients with Brugada-pattern electrocardiogram (ECG) underwent comprehensive genetic analysis of BrS-causing genes including SCN5A, SCN1B, SCN3B, CACNA1C, CACNB2, KCNE3 and KCNE5. 22987075

2012
Entrez Id: 10008
Gene Symbol: KCNE3
KCNE3
CUI: C1142166
Disease: Brugada Syndrome (disorder)
Brugada Syndrome (disorder) 		0.510 Biomarker GENOMICS_ENGLAND Novel KCNE3 mutation reduces repolarizing potassium current and associated with long QT syndrome. 19306396

2009
Entrez Id: 10008
Gene Symbol: KCNE3
KCNE3
CUI: C1142166
Disease: Brugada Syndrome (disorder)
Brugada Syndrome (disorder) 		0.510 Biomarker CLINGEN These results provide definitive evidence for a functional role of KCNE3 in the modulation of I(to) in the human heart and suggest that mutations in KCNE3 can underlie the development of BrS. 19122847

2008
Entrez Id: 10008
Gene Symbol: KCNE3
KCNE3
CUI: C1142166
Disease: Brugada Syndrome (disorder)
Brugada Syndrome (disorder) 		0.510 Biomarker CLINGEN Expression of multiple KCNE genes in human heart may enable variable modulation of I(Ks). 15698834

2005