Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 29927
Gene Symbol: SEC61A1
SEC61A1
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		0.410 Biomarker GENOMICS_ENGLAND Taken together, these findings provide a mechanism by which mutations in SEC61A1 lead to an autosomal-dominant syndromic form of progressive chronic kidney disease. 27392076

2016
Entrez Id: 3934
Gene Symbol: LCN2
LCN2
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		0.400 Biomarker CTD_human Interleukin-19 as a translational indicator of renal injury. 24714768

2015
Entrez Id: 353
Gene Symbol: APRT
APRT
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		0.390 Biomarker GENOMICS_ENGLAND Adenine phosphoribosyltransferase (APRT) deficiency is a rare autosomal recessive disorder characterized by 2,8-dihydroxyadenine (2,8-DHA) crystalluria that can cause nephrolithiasis and chronic kidney disease. 22212387

2012
Entrez Id: 56729
Gene Symbol: RETN
RETN
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		0.340 Biomarker CTD_human Correlates of resistin in children with chronic kidney disease: the chronic kidney disease in children cohort. 22421264

2012
Entrez Id: 8639
Gene Symbol: AOC3
AOC3
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		0.330 Biomarker CTD_human VAP-1, a novel molecule linked to endothelial damage and kidney function in kidney allograft recipients. 23154672

2012
Entrez Id: 4502
Gene Symbol: MT2A
MT2A
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		0.310 Biomarker CTD_human We aimed to elucidate associations between MT2A A-5G and risks of 2 diseases potentially related to lowered MT expression, chronic kidney disease (CKD), and diabetes mellitus (DM), in a community-dwelling population. 27122239

2016
Entrez Id: 29949
Gene Symbol: IL19
IL19
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		0.310 Biomarker CTD_human Interleukin-19 as a translational indicator of renal injury. 24714768

2015
Entrez Id: 22909
Gene Symbol: FAN1
FAN1
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		0.310 Biomarker GENOMICS_ENGLAND FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair. 22772369

2012
Entrez Id: 23552
Gene Symbol: CDK20
CDK20
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		0.300 Biomarker GENOMICS_ENGLAND Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment. 29773874

2018
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases 		0.300 Biomarker CTD_human Nerve growth factor serum concentrations increase during many inflammatory and autoimmune diseases, glomerulonephritis, chronic kidney disease, end-stage renal disease and, particularly, in renal transplant. 24244623

2013