DisGeNET - a database of gene-disease associations

Source: CURATED

Disease: Liver carcinoma ×

Gene: NR1H4 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	9971
Gene Symbol:	NR1H4

NR1H4

CUI:	C2239176
Disease:	Liver carcinoma

Liver carcinoma

0.530

Biomarker

CTD_human

Farnesoid X receptor antagonizes JNK signaling pathway in liver carcinogenesis by activating SOD3.

25496033

2015

Entrez Id:	9971
Gene Symbol:	NR1H4

NR1H4

CUI:	C2239176
Disease:	Liver carcinoma

Liver carcinoma

0.530

Biomarker

CTD_human

Small heterodimer partner overexpression partially protects against liver tumor development in farnesoid X receptor knockout mice.

23811326

2013