Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis 		0.400 Biomarker CTD_human In vivo cytochrome P450 activity alterations in diabetic nonalcoholic steatohepatitis mice. 27712037

2017
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis 		0.400 Biomarker CTD_human Stevia-derived compounds attenuate the toxic effects of ectopic lipid accumulation in the liver of obese mice: a transcriptomic and metabolomic study. 25554529

2015
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis 		0.400 Biomarker CTD_human Increased HO-1 levels ameliorate fatty liver development through a reduction of heme and recruitment of FGF21. 23839791

2014
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis 		0.400 Biomarker CTD_human Chronic exposure to low doses of pharmaceuticals disturbs the hepatic expression of circadian genes in lean and obese mice. 24525044

2014
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis 		0.400 Biomarker CTD_human A small molecule that blocks fat synthesis by inhibiting the activation of SREBP. 19716478

2009
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis 		0.400 Biomarker CTD_human Leptin may play a role in tamoxifen-induced hepatic steatosis. 12661780

2003