DisGeNET - a database of gene-disease associations

Source: GWASCAT

Disease: Intelligence ×

Gene: SHANK3 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	85358
Gene Symbol:	SHANK3

SHANK3

CUI:	C0021704
Disease:	Intelligence

Intelligence

0.100

GeneticVariation

GWASCAT

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.

31374203

2019

Entrez Id:	85358
Gene Symbol:	SHANK3

SHANK3

CUI:	C0021704
Disease:	Intelligence

Intelligence

0.100

GeneticVariation

GWASCAT

A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.

29326435

2019

Entrez Id:	85358
Gene Symbol:	SHANK3

SHANK3

CUI:	C0021704
Disease:	Intelligence

Intelligence

0.100

GeneticVariation

GWASCAT

Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals.

29520040

2019

Entrez Id:	85358
Gene Symbol:	SHANK3

SHANK3

CUI:	C0021704
Disease:	Intelligence

Intelligence

0.100

GeneticVariation

GWASCAT

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

29844566

2018