Source: GWASDB

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3664
Gene Symbol: IRF6
IRF6
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.900 GeneticVariation GWASDB Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. 22863734

2012
Entrez Id: 3664
Gene Symbol: IRF6
IRF6
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.900 GeneticVariation GWASDB SNPs near two genes not previously associated with cleft lip with and without cleft palate (MAFB, most significant SNP rs13041247, with odds ratio (OR) per minor allele = 0.704, 95% CI 0.635-0.778, P = 1.44 x 10(-11); and ABCA4, most significant SNP rs560426, with OR = 1.432, 95% CI 1.292-1.587, P = 5.01 x 10(-12)) and two previously identified regions (at chromosome 8q24 and IRF6) attained genome-wide significance. 20436469

2010
Entrez Id: 24
Gene Symbol: ABCA4
ABCA4
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.410 GeneticVariation GWASDB Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. 22863734

2012
Entrez Id: 24
Gene Symbol: ABCA4
ABCA4
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.410 GeneticVariation GWASDB SNPs near two genes not previously associated with cleft lip with and without cleft palate (MAFB, most significant SNP rs13041247, with odds ratio (OR) per minor allele = 0.704, 95% CI 0.635-0.778, P = 1.44 x 10(-11); and ABCA4, most significant SNP rs560426, with OR = 1.432, 95% CI 1.292-1.587, P = 5.01 x 10(-12)) and two previously identified regions (at chromosome 8q24 and IRF6) attained genome-wide significance. 20436469

2010
Entrez Id: 9423
Gene Symbol: NTN1
NTN1
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.110 GeneticVariation GWASDB Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. 22863734

2012
Entrez Id: 9423
Gene Symbol: NTN1
NTN1
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.110 GeneticVariation GWASDB A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4. 20436469

2010
Entrez Id: 2042
Gene Symbol: EPHA3
EPHA3
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation GWASDB Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. 22863734

2012
Entrez Id: 255928
Gene Symbol: SYT14
SYT14
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation GWASDB Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. 22863734

2012
Entrez Id: 23677
Gene Symbol: SH3BP4
SH3BP4
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation GWASDB Genome wide study of maternal and parent-of-origin effects on the etiology of orofacial clefts. 22419666

2012
Entrez Id: 57698
Gene Symbol: SHTN1
SHTN1
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation GWASDB Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. 22863734

2012
Entrez Id: 84319
Gene Symbol: CMSS1
CMSS1
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation GWASDB Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. 22863734

2012
Entrez Id: 137196
Gene Symbol: CCDC26
CCDC26
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation GWASDB Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. 22863734

2012
Entrez Id: 7546
Gene Symbol: ZIC2
ZIC2
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation GWASDB Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. 22863734

2012
Entrez Id: 5081
Gene Symbol: PAX7
PAX7
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation GWASDB Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. 22863734

2012
Entrez Id: 63892
Gene Symbol: THADA
THADA
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation GWASDB Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. 22863734

2012
Entrez Id: 27042
Gene Symbol: UTP25
UTP25
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation GWASDB Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. 22863734

2012
Entrez Id: 10507
Gene Symbol: SEMA4D
SEMA4D
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation GWASDB Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. 22863734

2012
Entrez Id: 9411
Gene Symbol: ARHGAP29
ARHGAP29
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation GWASDB Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. 22863734

2012
Entrez Id: 11259
Gene Symbol: FILIP1L
FILIP1L
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation GWASDB Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. 22863734

2012
Entrez Id: 80342
Gene Symbol: TRAF3IP3
TRAF3IP3
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation GWASDB Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. 22863734

2012
Entrez Id: 57544
Gene Symbol: TXNDC16
TXNDC16
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation GWASDB Genome wide study of maternal and parent-of-origin effects on the etiology of orofacial clefts. 22419666

2012
Entrez Id: 84830
Gene Symbol: ADTRP
ADTRP
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation GWASDB Evidence for gene-environment interaction in a genome wide study of nonsyndromic cleft palate. 21618603

2011
Entrez Id: 57698
Gene Symbol: SHTN1
SHTN1
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation GWASDB Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate. 20023658

2010
Entrez Id: 57698
Gene Symbol: SHTN1
SHTN1
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation GWASDB A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4. 20436469

2010
Entrez Id: 255928
Gene Symbol: SYT14
SYT14
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip 		0.100 GeneticVariation GWASDB A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4. 20436469

2010