Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8633
Gene Symbol: UNC5C
UNC5C
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.360 GeneticVariation UNIPROT An Alzheimer Disease-linked Rare Mutation Potentiates Netrin Receptor Uncoordinated-5C-induced Signaling That Merges with Amyloid β Precursor Protein Signaling. 27068745

2016

Entrez Id: 8633
Gene Symbol: UNC5C
UNC5C
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.360 GeneticVariation UNIPROT On the basis of these data and the enriched hippocampal expression of UNC5C in the adult nervous system, we propose that one possible mechanism in which T835M UNC5C contributes to the risk of Alzheimer's disease is by increasing susceptibility to neuronal cell death, particularly in vulnerable regions of the Alzheimer's disease brain. 25419706

2014