×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Cardiomyopathy, Familial Idiopathic
1.000
GeneticVariation
UNIPROT
LMNA mutations represent the most prevalent genetic DCM cause.
21846512
2012
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Cardiomyopathy, Familial Idiopathic
1.000
GeneticVariation
UNIPROT
Morphological analysis of 13 LMNA variants identified in a cohort of 324 unrelated patients with idiopathic or familial dilated cardiomyopathy.
20160190
2010
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Cardiomyopathy, Familial Idiopathic
1.000
GeneticVariation
UNIPROT
Dilated cardiomyopathy with profound segmental wall motion abnormalities and ventricular arrhythmia caused by the R541C mutation in the LMNA gene.
19167105
2010
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Cardiomyopathy, Familial Idiopathic
1.000
GeneticVariation
UNIPROT
Sumoylation regulates lamin A function and is lost in lamin A mutants associated with familial cardiomyopathies.
18606848
2008
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Cardiomyopathy, Familial Idiopathic
1.000
GeneticVariation
UNIPROT
Our in vivo and in vitro results question the relationship of causality between LMNA mutations and the development of heart failure in some DCM patients and therefore, the reliability of genetic counselling.
16061563
2005
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Cardiomyopathy, Familial Idiopathic
1.000
GeneticVariation
UNIPROT
Nuclear envelope alterations in fibroblasts from patients with muscular dystrophy, cardiomyopathy, and partial lipodystrophy carrying lamin A/C gene mutations.
15372542
2004
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Cardiomyopathy, Familial Idiopathic
1.000
GeneticVariation
UNIPROT
Familial dilated cardiomyopathy and isolated left ventricular noncompaction associated with lamin A/C gene mutations.
15219508
2004
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Cardiomyopathy, Familial Idiopathic
1.000
GeneticVariation
UNIPROT
A novel mutation S143P in the lamin A/C gene was found to be common among Finnish DCM patients.
15140538
2004
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Cardiomyopathy, Familial Idiopathic
1.000
GeneticVariation
UNIPROT
Mutations in the lamin A/C gene (LMNA) have been reported to be involved in dilated cardiomyopathy (DCM ) associated with conduction system disease and/or skeletal myopathy.
12920062
2003
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Cardiomyopathy, Familial Idiopathic
1.000
GeneticVariation
UNIPROT
Mutation analysis of the lamin A/C gene (LMNA) among patients with different cardiomuscular phenotypes.
14684700
2003
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Cardiomyopathy, Familial Idiopathic
1.000
GeneticVariation
UNIPROT
Apical left ventricular aneurysm without atrio-ventricular block due to a lamin A/C gene mutation.
14675861
2003
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Cardiomyopathy, Familial Idiopathic
1.000
GeneticVariation
UNIPROT
We examined the prevalence, genotype-phenotype correlation, and natural history of lamin A/C gene (LMNA) mutations in subjects with dilated cardiomyopathy (DCM ).
12628721
2003
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Cardiomyopathy, Familial Idiopathic
1.000
GeneticVariation
UNIPROT
A novel lamin A/C mutation in a family with dilated cardiomyopathy, prominent conduction system disease, and need for permanent pacemaker implantation.
12486434
2002
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Cardiomyopathy, Familial Idiopathic
1.000
GeneticVariation
UNIPROT
Five novel LMNA mutations (K97E, E111X, R190W, E317K, four base pair insertion at 1,713 cDNA) were identified in five cases of familial autosomal dominant DCM with AVB (5/15: 33%).
11897440
2002
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Cardiomyopathy, Familial Idiopathic
1.000
GeneticVariation
UNIPROT
Novel lamin A/C mutations in two families with dilated cardiomyopathy and conduction system disease.
11561226
2001
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Cardiomyopathy, Familial Idiopathic
1.000
GeneticVariation
UNIPROT
Properties of lamin A mutants found in Emery-Dreifuss muscular dystrophy, cardiomyopathy and Dunnigan-type partial lipodystrophy.
11792809
2001
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Cardiomyopathy, Familial Idiopathic
1.000
GeneticVariation
UNIPROT
Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease.
10580070
1999