Source: CURATED

Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs11196205
rs11196205
TCF7L2
0.827 0.200 10 113047288 intron variant G/A;C;T snv
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.800 0.917 0 2006 2020
dbSNP: rs137853240
rs137853240
HNF1A
0.807 0.080 12 120994405 missense variant G/A snv 1.4E-05
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.800 0.917 0 2000 2011
dbSNP: rs3792267
rs3792267
CAPN10
0.882 0.200 2 240591757 non coding transcript exon variant G/A snv 0.23
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.770 0.857 0 2006 2016
dbSNP: rs137852783
rs137852783
PDX1
0.882 0.080 13 27920364 missense variant G/A;T snv 2.9E-03
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.760 0.833 0 2000 2015
dbSNP: rs2975760
rs2975760
CAPN10
1.000 0.080 2 240591746 non coding transcript exon variant T/C snv 0.12
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.730 1.000 0 2006 2014
dbSNP: rs5030952
rs5030952
CAPN10
0.925 0.160 2 240603286 intron variant C/G;T snv
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.730 1.000 0 2010 2013
dbSNP: rs137852786
rs137852786
PDX1
1.000 0.080 13 27924439 missense variant G/A snv
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.720 1.000 0 1999 2002
dbSNP: rs3842570
rs3842570
CAPN10
0.925 0.160 2 240594824 intron variant -/CGGGAGGAGGGTGATGATTCTGTCCCAGGAGC delins
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.720 1.000 0 2010 2011
dbSNP: rs104893642
rs104893642
IRS1
1.000 0.080 2 226796916 missense variant G/A;C snv 1.5E-05; 5.0E-06
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.710 1.000 0 2003 2003
dbSNP: rs137852785
rs137852785
PDX1
0.925 0.080 13 27920190 missense variant T/C snv 1.1E-04 1.0E-04
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.710 1.000 0 2002 2002
dbSNP: rs200998587
rs200998587
RBPJL
0.925 0.080 20 45314116 missense variant C/T snv 1.7E-03 4.0E-04
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.710 1.000 0 2018 2018
dbSNP: rs2070895
rs2070895
LIPC ; ALDH1A2
0.807 0.120 15 58431740 intron variant G/A snv 0.33
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.710 1.000 0 2008 2008
dbSNP: rs121918407
rs121918407
GPD2
1.000 0.080 2 156579109 missense variant T/A;C snv
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 0
dbSNP: rs1259467443
rs1259467443
IRS1
1.000 0.080 2 226796570 inframe deletion ACC/- delins 8.0E-06 7.0E-06
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 0
dbSNP: rs1339616347
rs1339616347
WRN
0.925 0.120 8 31068328 splice donor variant G/T snv
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 0
dbSNP: rs1360415315
rs1360415315
GCK ; LOC105375258
0.851 0.080 7 44149772 missense variant C/G;T snv 4.0E-06
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 0
dbSNP: rs137852673
rs137852673
ABCC8
0.851 0.120 11 17395915 missense variant G/A;T snv 5.0E-06; 2.0E-05
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 0
dbSNP: rs137852674
rs137852674
ABCC8
0.925 0.120 11 17430887 missense variant G/C snv
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 0
dbSNP: rs137852784
rs137852784
PDX1
0.925 0.080 13 27920314 missense variant A/T snv 1.5E-05 1.4E-05
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 0
dbSNP: rs137853236
rs137853236
HNF1A
0.807 0.280 12 120997504 missense variant C/T snv 1.2E-05
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 0
dbSNP: rs141804752
rs141804752
MTNR1B
1.000 0.080 11 92969904 missense variant T/A;G snv 2.0E-05; 3.2E-04
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 0
dbSNP: rs148311934
rs148311934
GCK ; LOC105375258
0.827 0.080 7 44149763 missense variant C/T snv 8.0E-06 1.4E-05
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 0
dbSNP: rs1553638903
rs1553638903
PPARG
1.000 0.080 3 12349804 intron variant A/G snv
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 0
dbSNP: rs1553638909
rs1553638909
PPARG
1.000 0.080 3 12349824 intron variant A/T snv
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 0
dbSNP: rs1553784995
rs1553784995
SLC2A2
1.000 0.080 3 170998236 stop gained C/T snv
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 0