Source: ALL

Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs4986790
rs4986790
TLR4
0.438 0.800 9 117713024 missense variant A/G;T snv 6.1E-02; 4.0E-06
CUI: C0577631
Disease: Carotid Atherosclerosis
Carotid Atherosclerosis 		0.040 0.750 4 2003 2007
dbSNP: rs4986790
rs4986790
TLR4
0.438 0.800 9 117713024 missense variant A/G;T snv 6.1E-02; 4.0E-06
CUI: C0242383
Disease: Age related macular degeneration
Age related macular degeneration 		0.040 0.250 4 2005 2009
dbSNP: rs4986790
rs4986790
TLR4
0.438 0.800 9 117713024 missense variant A/G;T snv 6.1E-02; 4.0E-06
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.040 0.750 4 2004 2016
dbSNP: rs4986790
rs4986790
TLR4
0.438 0.800 9 117713024 missense variant A/G;T snv 6.1E-02; 4.0E-06
CUI: C0850666
Disease: Infection caused by Helicobacter pylori
Infection caused by Helicobacter pylori 		0.040 1.000 4 2012 2019
dbSNP: rs4986790
rs4986790
TLR4
0.438 0.800 9 117713024 missense variant A/G;T snv 6.1E-02; 4.0E-06
CUI: C0266929
Disease: Chronic Periodontitis
Chronic Periodontitis 		0.040 0.750 4 2007 2016
dbSNP: rs4986790
rs4986790
TLR4
0.438 0.800 9 117713024 missense variant A/G;T snv 6.1E-02; 4.0E-06
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.040 1.000 4 2011 2018
dbSNP: rs4986790
rs4986790
TLR4
0.438 0.800 9 117713024 missense variant A/G;T snv 6.1E-02; 4.0E-06
CUI: C0019163
Disease: Hepatitis B
Hepatitis B 		0.040 0.750 4 2012 2019
dbSNP: rs4986790
rs4986790
TLR4
0.438 0.800 9 117713024 missense variant A/G;T snv 6.1E-02; 4.0E-06
CUI: C0017152
Disease: Gastritis
Gastritis 		0.040 1.000 4 2007 2019
dbSNP: rs4986790
rs4986790
TLR4
0.438 0.800 9 117713024 missense variant A/G;T snv 6.1E-02; 4.0E-06
CUI: C0042029
Disease: Urinary tract infection
Urinary tract infection 		0.040 1.000 4 2018 2020
dbSNP: rs4986791
rs4986791
TLR4
0.456 0.840 9 117713324 missense variant C/T snv 5.7E-02 4.9E-02
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.040 0.750 4 2004 2012
dbSNP: rs4986791
rs4986791
TLR4
0.456 0.840 9 117713324 missense variant C/T snv 5.7E-02 4.9E-02
CUI: C0339573
Disease: Glaucoma, Primary Open Angle
Glaucoma, Primary Open Angle 		0.040 0.750 4 2016 2020
dbSNP: rs4986791
rs4986791
TLR4
0.456 0.840 9 117713324 missense variant C/T snv 5.7E-02 4.9E-02
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.040 0.500 4 2011 2018
dbSNP: rs4986791
rs4986791
TLR4
0.456 0.840 9 117713324 missense variant C/T snv 5.7E-02 4.9E-02
CUI: C0850666
Disease: Infection caused by Helicobacter pylori
Infection caused by Helicobacter pylori 		0.040 1.000 4 2012 2019
dbSNP: rs4986791
rs4986791
TLR4
0.456 0.840 9 117713324 missense variant C/T snv 5.7E-02 4.9E-02
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.040 0.500 4 2006 2018
dbSNP: rs4986791
rs4986791
TLR4
0.456 0.840 9 117713324 missense variant C/T snv 5.7E-02 4.9E-02
CUI: C0042029
Disease: Urinary tract infection
Urinary tract infection 		0.040 0.750 4 2013 2020
dbSNP: rs11536889
rs11536889
TLR4
0.658 0.560 9 117715853 3 prime UTR variant G/C snv 0.11
CUI: C0699791
Disease: Stomach Carcinoma
Stomach Carcinoma 		0.030 1.000 3 2011 2014
dbSNP: rs11536889
rs11536889
TLR4
0.658 0.560 9 117715853 3 prime UTR variant G/C snv 0.11
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.030 1.000 3 2011 2014
dbSNP: rs11536889
rs11536889
TLR4
0.658 0.560 9 117715853 3 prime UTR variant G/C snv 0.11
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.030 1.000 3 2016 2019
dbSNP: rs1927911
rs1927911
TLR4
0.658 0.640 9 117707776 intron variant A/G snv 0.62
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.030 1.000 3 2013 2015
dbSNP: rs1927914
rs1927914
TLR4
0.732 0.520 9 117702447 upstream gene variant G/A snv 0.52
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.030 1.000 3 2013 2015
dbSNP: rs4986790
rs4986790
TLR4
0.438 0.800 9 117713024 missense variant A/G;T snv 6.1E-02; 4.0E-06
CUI: C0036202
Disease: Sarcoidosis
Sarcoidosis 		0.030 1.000 3 2006 2009
dbSNP: rs4986790
rs4986790
TLR4
0.438 0.800 9 117713024 missense variant A/G;T snv 6.1E-02; 4.0E-06
CUI: C0004623
Disease: Bacterial Infections
Bacterial Infections 		0.030 1.000 3 2006 2010
dbSNP: rs4986790
rs4986790
TLR4
0.438 0.800 9 117713024 missense variant A/G;T snv 6.1E-02; 4.0E-06
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.030 1.000 3 2008 2014
dbSNP: rs4986790
rs4986790
TLR4
0.438 0.800 9 117713024 missense variant A/G;T snv 6.1E-02; 4.0E-06
CUI: C0039483
Disease: Giant Cell Arteritis
Giant Cell Arteritis 		0.030 0.667 3 2010 2014
dbSNP: rs4986790
rs4986790
TLR4
0.438 0.800 9 117713024 missense variant A/G;T snv 6.1E-02; 4.0E-06
CUI: C0001339
Disease: Acute pancreatitis
Acute pancreatitis 		0.030 0.667 3 2007 2014