Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4986791
rs4986791
TLR4
CUI: C0339573
Disease: Glaucoma, Primary Open Angle
Glaucoma, Primary Open Angle 		0.040 GeneticVariation BEFREE The minor alleles of rs4986791 and rs2149356 within TLR4 gene, interaction between rs2149356 and alcohol drinking were all associated with increased POAG risk. 31697008

2020
dbSNP: rs4986791
rs4986791
TLR4
CUI: C0339573
Disease: Glaucoma, Primary Open Angle
Glaucoma, Primary Open Angle 		0.040 GeneticVariation BEFREE Moreover, rs4986790 A/G and rs4986791 C/T showed a stringent association with POAG in allele contrast, heterozygous, recessive, and overdominant models. 30877182

2019
dbSNP: rs4986791
rs4986791
TLR4
CUI: C0339573
Disease: Glaucoma, Primary Open Angle
Glaucoma, Primary Open Angle 		0.040 GeneticVariation BEFREE TLR4 coding SNPs Asp299Gly and Thr399Ile might be used as genetic susceptibility alleles for POAG in Mexican population. 28214954

2017
dbSNP: rs4986791
rs4986791
TLR4
CUI: C0339573
Disease: Glaucoma, Primary Open Angle
Glaucoma, Primary Open Angle 		0.040 GeneticVariation BEFREE We did not detect any direct association between genotypes or allele frequencies of SNP rs4986791 in the TLR4 gene and POAG. 27526043

2016