Source: CLINVAR

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121912666
rs121912666
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		G 0.800 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121912666
rs121912666
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		C 0.800 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs113488022
rs113488022
BRAF
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		T 0.800 GeneticVariation CLINVAR Targeted therapy for BRAFV600E malignant astrocytoma. 22038996

2011
dbSNP: rs113488022
rs113488022
BRAF
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		T 0.800 GeneticVariation CLINVAR Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy. 22586120

2012
dbSNP: rs113488022
rs113488022
BRAF
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		T 0.800 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121913500
rs121913500
IDH1
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		T 0.790 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121913500
rs121913500
IDH1
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		T 0.790 GeneticVariation CLINVAR An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. 23558169

2013
dbSNP: rs121913500
rs121913500
IDH1
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		A 0.790 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121913343
rs121913343
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		T 0.710 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs985033810
rs985033810
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs985033810
rs985033810
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs967461896
rs967461896
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		G 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs967461896
rs967461896
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		C 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs942158624
rs942158624
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs876660821
rs876660821
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		C 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs876660754
rs876660754
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs876660754
rs876660754
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs876659802
rs876659802
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs876659675
rs876659675
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		C 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs876658468
rs876658468
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs876658468
rs876658468
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs876658468
rs876658468
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		C 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs866775781
rs866775781
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		G 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs863224451
rs863224451
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs863224451
rs863224451
TP53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		T 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016