|
rs1805087
|
|
Ventricular Septal Defects
|
|
0.010 |
GeneticVariation
|
BEFREE |
We investigated whether a polymorphism (A2756G) of the methionine synthase and 2 polymorphisms (A66G and C524T) of the MTRR gene are associated with VSDs.
|
29293099 |
2019 |
|
rs1805087
|
|
Multiple Sclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Relationship between genetic polymorphisms MTHFR (C677T, A1298C), MTR (A2756G) and MTRR (A66G) genes and multiple sclerosis: a case-control study.
|
31038186 |
2019 |
|
rs1805087
|
|
Autism Spectrum Disorders
|
|
0.010 |
GeneticVariation
|
BEFREE |
MATERIAL AND METHODS Genotypes of transcobalamin 2 (TCN2) rs1801198, methionine synthase (MTR) rs1805087, methionine synthase reductase (MTRR) rs1801394, and methylene tetrahydrofolate reductase (MTHFR) rs1801133 were examined in 201 children with ASD and 200 healthy controls from the Han Chinese population.
|
29348398 |
2018 |
|
rs1805087
|
|
Abnormal behavior
|
|
0.010 |
GeneticVariation
|
BEFREE |
While rs1051266, rs1801131, and rs1805087 showed association with behavioral problems, rs3733890 was associated with ODD score.
|
29407547 |
2018 |
|
rs1805087
|
|
Early childhood caries
|
|
0.010 |
GeneticVariation
|
BEFREE |
The present study aimed to evaluate the association of polymorphisms in genes MTR (rs1805087) and MTRR (rs1801394) with susceptibility of early childhood caries (ECC) and with body mass index alterations.
|
28118645 |
2017 |
|
rs1805087
|
|
Inattention
|
|
0.010 |
GeneticVariation
|
BEFREE |
Probands having rs1805087 'GG' and rs1051266 'G' was more inattentive.
|
28250422 |
2017 |
|
rs1805087
|
|
Varicosity
|
|
0.010 |
GeneticVariation
|
BEFREE |
The objective of this study was to study the association of polymorphisms MTHFR C677T (rs1801133) and MTR A2756G (rs1805087) with the risk of varicose veins in ethnical Russians.
|
27097558 |
2016 |
|
rs1805087
|
|
Hypertriglyceridemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
Each of four gene polymorphisms (MTHTR C677T, MTHFR A1298C, MTR A2756G and MTRR A66G) combined with low folate showed higher odds of hypertriglyceridemia (P for trend: 0.049, 0.004, 0.007 and 0.005, respectively).
|
26337056 |
2015 |
|
rs1805087
|
|
Turner Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
The polymorphisms MTHFR 677C>T and 1298A>C, MTR 2756A>G, RFC1 80G>A, and TYMS 2R/3R-alone or in combinations-were not associated with the risk of chromosomal aneuploidy in TS.
|
25858821 |
2015 |
|
rs1805087
|
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
We aim to investigate the effects of homocysteine metabolism enzyme polymorphisms (MTHTR C677T, MTHFR A1298C, MTR A2756G and MTRR A66G) and their interactions with folate, homocysteine on serum lipid levels in Chinese patients with hypertension.
|
26337056 |
2015 |
|
rs1805087
|
|
Adult Non-Hodgkin Lymphoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
No association between MTR rs1805087 A > G polymorphism and non-Hodgkin lymphoma susceptibility: evidence from 11 486 subjects.
|
24956146 |
2015 |
|
rs1805087
|
|
Azoospermia
|
|
0.010 |
GeneticVariation
|
BEFREE |
The polymorphic distributions of the four SNPs (MTHFR C677T and A1298C, MTR A2756G and MTRR A66G) were investigated by the method of SNaPshot in a Chinese cohort including 296 idiopathic infertile males with azoospermia or oligozoospermia and 204 fertile males.
|
25578539 |
2015 |
|
rs1805087
|
|
Oligospermia
|
|
0.010 |
GeneticVariation
|
BEFREE |
The polymorphic distributions of the four SNPs (MTHFR C677T and A1298C, MTR A2756G and MTRR A66G) were investigated by the method of SNaPshot in a Chinese cohort including 296 idiopathic infertile males with azoospermia or oligozoospermia and 204 fertile males.
|
25578539 |
2015 |
|
rs1805087
|
|
Dyslipidemias
|
|
0.010 |
GeneticVariation
|
BEFREE |
Low folate status and homocysteine metabolism gene polymorphisms (MTHTR C677T, MTHFR A1298C, MTR A2756G and MTRR A66G) may have a synergistic effect increased the incidence of dyslipidemia in Chinese hypertensive population.
|
26337056 |
2015 |
|
rs1805087
|
|
Childhood Non-Hodgkin Lymphoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
No association between MTR rs1805087 A > G polymorphism and non-Hodgkin lymphoma susceptibility: evidence from 11 486 subjects.
|
24956146 |
2015 |
|
rs1805087
|
|
Mild cognitive disorder
|
|
0.010 |
GeneticVariation
|
BEFREE |
Multivariate logistic regression showed that, in addition to the well-known risk factors, such as low education level, high cholesterol level, high level of low-density lipoprotein, and high homocysteine levels, the A>G mutation in the MS gene at the rs1805087 locus was another independent risk factor for MCI in the Uyghur MCI population.
|
25625218 |
2015 |
|
rs1805087
|
|
Lymphoma, Non-Hodgkin, Familial
|
|
0.010 |
GeneticVariation
|
BEFREE |
No association between MTR rs1805087 A > G polymorphism and non-Hodgkin lymphoma susceptibility: evidence from 11 486 subjects.
|
24956146 |
2015 |
|
rs1805087
|
|
Malignant neoplasm of liver
|
|
0.010 |
GeneticVariation
|
BEFREE |
In addition, we detected potential heterogeneity across alcohol drinking status for ORs relating MTRR rs1801394 to esophageal (posterior homogeneity P = 0.005) and stomach cancer (posterior homogeneity P = 0.004), and ORs relating MTR rs1805087 to liver cancer (posterior homogeneity P = 0.021).
|
25337902 |
2014 |
|
rs1805087
|
|
Central neuroblastoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of this study was to investigate whether the genetic polymorphisms MTHFR C677T and A1298C, MTR A2756G, TYMS 2R/3R and SLC19A1 G80A, involved in folate metabolism, increase the risk of neuroblastoma in Brazilian children.
|
24771227 |
2014 |
|
rs1805087
|
|
Neuroblastoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of this study was to investigate whether the genetic polymorphisms MTHFR C677T and A1298C, MTR A2756G, TYMS 2R/3R and SLC19A1 G80A, involved in folate metabolism, increase the risk of neuroblastoma in Brazilian children.
|
24771227 |
2014 |
|
rs1805087
|
|
Liver and Intrahepatic Biliary Tract Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
In addition, we detected potential heterogeneity across alcohol drinking status for ORs relating MTRR rs1801394 to esophageal (posterior homogeneity P = 0.005) and stomach cancer (posterior homogeneity P = 0.004), and ORs relating MTR rs1805087 to liver cancer (posterior homogeneity P = 0.021).
|
25337902 |
2014 |
|
rs1805087
|
|
Adult Liver Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
In addition, we detected potential heterogeneity across alcohol drinking status for ORs relating MTRR rs1801394 to esophageal (posterior homogeneity P = 0.005) and stomach cancer (posterior homogeneity P = 0.004), and ORs relating MTR rs1805087 to liver cancer (posterior homogeneity P = 0.021).
|
25337902 |
2014 |
|
rs1805087
|
|
Childhood Neuroblastoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of this study was to investigate whether the genetic polymorphisms MTHFR C677T and A1298C, MTR A2756G, TYMS 2R/3R and SLC19A1 G80A, involved in folate metabolism, increase the risk of neuroblastoma in Brazilian children.
|
24771227 |
2014 |
|
rs1805087
|
|
Cervix carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
No effects of MTHFR C677T polymorphism on CIN II/III risk and MTHFR A1298C or MS A2756G polymorphisms on cervical cancer risk were detected.
|
23864153 |
2013 |
|
rs1805087
|
|
Meniere Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Multiple logistic regression was used to calculate odds ratios (ORs) for SSNHL and Ménière's disease in individuals with polymorphisms in the genes: methionine synthase (MTR; rs1805087); methionine-synthase reductase (MTRR; rs1801394); nitric oxide synthase 3 (NOS3; rs1799983); caveolin 1 (Cav1; rs3840634); melatonin receptor 1B (MTNR1B; rs1387153); NAD(P)H oxidase p22(phox) subunit (NADH/NADPHp22phox; rs4673); and mitochondria 5178 (MT5178; rs28357984).
|
23560644 |
2013 |