|
rs72551362
|
|
Endothelial dysfunction
|
|
0.030 |
GeneticVariation
|
BEFREE |
Endothelial dysfunction in the basilar artery from E-V290M mice fed low salt was attenuated by scavengers of superoxide, inhibitors of NADPH oxidase, or blockade of the Ang II AT1 (angiotensin type-1) receptor.
|
30354810 |
2018 |
|
rs72551362
|
|
Endothelial dysfunction
|
|
0.030 |
GeneticVariation
|
BEFREE |
Endothelial dysfunction in angiotensin II-treated E-V290M vasopressin-exposed offspring was attenuated by tempol, an effect which was more prominent in male offspring.
|
31104564 |
2019 |
|
rs910042982
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
Endothelial dysfunction in angiotensin II-treated E-V290M vasopressin-exposed offspring was attenuated by tempol, an effect which was more prominent in male offspring.
|
31104564 |
2019 |
|
rs1217691063
|
|
Endothelial dysfunction
|
|
0.070 |
GeneticVariation
|
BEFREE |
C677T polymorphism in methylenetetrahydrofolate reductase gene (MTHFR) is a major determinant of hyperhomocysteinemia, which results in endothelial dysfunction.
|
15226090 |
2004 |
|
rs1217691063
|
|
Endothelial dysfunction
|
|
0.070 |
GeneticVariation
|
BEFREE |
A slight chronic hypoperfusion or an endothelial dysfunction associated with unfavorable genetic variations such as methylenetetrahydrofolate reductase C677T variation and angiotensin-converting enzyme I/D polymorphism then may lead indirectly to a malfunction of the molecular cross-talk between the nucleus and the mitochondria.
|
17114822 |
2007 |
|
rs1217691063
|
|
Endothelial dysfunction
|
|
0.070 |
GeneticVariation
|
BEFREE |
Also, no association between the MTHFR 677 C>T polymorphism and CV events or endothelial dysfunction was observed.
|
20423475 |
2010 |
|
rs1217691063
|
|
Endothelial dysfunction
|
|
0.070 |
GeneticVariation
|
BEFREE |
An increasing body of evidence suggests that different genetic factors, such as angiotensin-converting enzyme (ACE) I/D, angiotensin II type-1 receptor (AT1R) A1166C, methylenetetrahydrofolate reductase (MTHFR) C677T and ENOS G894T variants are associated with an endothelial dysfunction (ED).
|
17504188 |
2007 |
|
rs375752214
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
An increasing body of evidence suggests that different genetic factors, such as angiotensin-converting enzyme (ACE) I/D, angiotensin II type-1 receptor (AT1R) A1166C, methylenetetrahydrofolate reductase (MTHFR) C677T and ENOS G894T variants are associated with an endothelial dysfunction (ED).
|
17504188 |
2007 |
|
rs1799983
|
|
Endothelial dysfunction
|
|
0.090 |
GeneticVariation
|
BEFREE |
An increasing body of evidence suggests that different genetic factors, such as angiotensin-converting enzyme (ACE) I/D, angiotensin II type-1 receptor (AT1R) A1166C, methylenetetrahydrofolate reductase (MTHFR) C677T and ENOS G894T variants are associated with an endothelial dysfunction (ED).
|
17504188 |
2007 |
|
rs1217691063
|
|
Endothelial dysfunction
|
|
0.070 |
GeneticVariation
|
BEFREE |
Angiotensin-converting enzyme (ACE) insertion (I)/deletion (D) and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphisms are linked to endothelial dysfunction and to cerebral white matter lesions.
|
19298544 |
2009 |
|
rs1799983
|
|
Endothelial dysfunction
|
|
0.090 |
GeneticVariation
|
BEFREE |
Association of endothelial dysfunction with endothelin, nitric oxide and eNOS Glu298Asp gene polymorphism in coronary artery disease.
|
22045428 |
2011 |
|
rs1217691063
|
|
Endothelial dysfunction
|
|
0.070 |
GeneticVariation
|
BEFREE |
Coexistence of homozygosity for the C677T mutation and B12 deficiency is associated with endothelial dysfunction and can be corrected with vitamin B12 and folic acid treatment.
|
17449548 |
2007 |
|
rs72551362
|
|
Endothelial dysfunction
|
|
0.030 |
GeneticVariation
|
BEFREE |
Conversely, IL-1β-induced endothelial dysfunction was worsened in the aorta from E-V290M mice.
|
26566726 |
2016 |
|
rs1799983
|
|
Endothelial dysfunction
|
|
0.090 |
GeneticVariation
|
BEFREE |
Genetic polymorphism G894T on endothelial nitric oxide synthase (eNOS) gene has been associated with endothelial dysfunction in young smokers, but its role in the pathogenesis of MI is obscure.
|
16337503 |
2006 |
|
rs1799983
|
|
Endothelial dysfunction
|
|
0.090 |
GeneticVariation
|
BEFREE |
In a population with a compromised endothelial function, concentrations of phenols in dietary VOO interact with NOS3 Glu298Asp to ameliorate the endothelial dysfunction associated to the TT genotype.
|
21816783 |
2011 |
|
rs1800629
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
In this regard, besides a strong association between the HLA-DRB1∗04 shared epitope alleles and both endothelial dysfunction, an early step in the atherosclerotic process, and clinically evident CV disease, other polymorphisms belonging to genes implicated in inflammatory and metabolic pathways, located inside and outside the HLA region, such as the 308 variant (G > A, rs1800629) of the TNFA locus, the rs1801131 polymorphism (A > C; position + 1298) of the MTHFR locus, or a deletion of 32 base pairs on the CCR5 gene, seem to be associated with the risk of CV disease in patients with RA.
|
22927710 |
2012 |
|
rs1217691063
|
|
Endothelial dysfunction
|
|
0.070 |
GeneticVariation
|
BEFREE |
It was aimed to explain the association of the endothelial dysfunction, which is thought to play a role in the pathophysiology of CSX, with C677T polymorphism on MTHFR gene based on genetic basis.
|
28481466 |
2018 |
|
rs753482
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
Measures of glucose tolerance, insulin sensitivity, markers of endothelial dysfunction, forearm vasodilation, and adipokine levels were determined and associated to the frequency of two single-nucleotide polymorphisms of NOS3, i.e., Glu298Asp (rs1799983, G/T) and rs753482 (intron 18 A/C).
|
18349107 |
2008 |
|
rs599839
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results confirm an association of the rs599839 polymorphism with endothelial dysfunction in RA.
|
22380622 |
2012 |
|
rs1799983
|
|
Endothelial dysfunction
|
|
0.090 |
GeneticVariation
|
BEFREE |
Polymorphisms in the endothelial nitric oxide synthase ( eNOS ) gene (- 786T > C and 894G > T ) enhance endothelial dysfunction and have been studied in relation to coronary artery disease (CAD).
|
20846926 |
2010 |
|
rs4961
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
Since inflammatory mechanisms may be involved in pathophysiology of hypertension and in endothelial dysfunction and atherosclerosis through reactive oxygen species, the baseline urinary excretion of inflammatory and oxidative stress markers in a subgroup of adolescents stratified according to <i>ADD1</i>(alpha adducin) rs4961 genotypes was assessed.
|
31760884 |
2020 |
|
rs876657421
|
|
Endothelial dysfunction
|
|
0.020 |
GeneticVariation
|
BEFREE |
Tg-I278T Cbs(-/-) mice exhibited severe hyperhomocysteinemia and endothelial dysfunction in cerebral arterioles.
|
22186991 |
2012 |
|
rs5742905
|
|
Endothelial dysfunction
|
|
0.020 |
GeneticVariation
|
BEFREE |
Tg-I278T Cbs(-/-) mice exhibited severe hyperhomocysteinemia and endothelial dysfunction in cerebral arterioles.
|
22186991 |
2012 |
|
rs1799983
|
|
Endothelial dysfunction
|
|
0.090 |
GeneticVariation
|
BEFREE |
The 894T allele of a G894T polymorphism in the endothelial nitric oxide synthase (eNOS) gene is associated with decreased eNOS activity, cleavage of the protein, and endothelial dysfunction.
|
11668050 |
2001 |
|
rs1056534
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of our study was to evaluate an association of FN3K (rs1056534, rs3848403) and GLO1 rs4746 polymorphisms with parameters of endothelial dysfunction and soluble receptor for AGEs (sRAGE) in 595 diabetic and non-diabetic subjects.
|
24908234 |
2014 |