DisGeNET - a database of gene-disease associations

Source: GWASCAT

Disease: Bilirubin measurement ×

Gene: UGT1A3 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs17864701

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3 ; DNAJB3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.700

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs2885296

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.700

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs28898617

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.700

GeneticVariation

GWASCAT

Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.

29403010

2018

dbSNP:

rs34352510

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.700

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs35754645

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3 ; LOC100286922

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.700

GeneticVariation

GWASCAT

Very low-depth whole-genome sequencing in complex trait association studies.

30576415

2019

dbSNP:

rs3771341

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.700

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs4477910

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.700

GeneticVariation

GWASCAT

Phenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols.

25884002

2015

dbSNP:

rs6747843

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3 ; LOC100286922

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.700

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs75520741

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.700

GeneticVariation

GWASCAT

Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.

29403010

2018

dbSNP:

rs10178992

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs10179091

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs10929301

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3 ; LOC100286922

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs10929302

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3 ; LOC100286922

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs11673726

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3 ; LOC100286922

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs11695484

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3 ; DNAJB3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs11888459

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A2P ; UGT1A9 ; UGT1A4 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs11891311

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

23371916

2013

dbSNP:

rs17862875

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs28946889

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.

29403010

2018

dbSNP:

rs3755319

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Phenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols.

25884002

2015

dbSNP:

rs4148323

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

23371916

2013

dbSNP:

rs4148323

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

The protein coding variant rs4148323, which is monomorphic in European-derived populations, may be specifically associated with serum bilirubin levels in Asians (P = 2.56 x 10(-70)).

20639394

2010

dbSNP:

rs4148324

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs4148325

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population.

30621171

2019

dbSNP:

rs4148325

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Phenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols.

25884002

2015