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rs1217691063
|
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Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
In infants with atypical PVHI mutation analysis of the factor V Leiden (G1691A), prothrombin (G20210A) gene, and C677T and A1298C polymorphisms in the MTHFR gene was performed, and plasma lipoprotein(a) and homocysteine levels were measured.
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22098125 |
2012 |
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rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
Factor V Leiden (G1691A), the prothrombin 3'-untranslated region variant (G20210A) and thermolabile methylenetetrahydrofolate reductase (C677T): a single genetic test genotypes all three loci--determination of frequencies in the S. Wales population of the UK.
|
9609227 |
1998 |
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rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
We report the case of a male newborn with left RVT and associated homozygosity for both factor V Leiden (G1691A) and methylenetetrahydrofolate reductase C677T mutations in addition to elevated serum lipoprotein (a).The patient was treated with heparin.
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19542880 |
2009 |
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rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
Newborn screening cards of 883 Caucasian babies born in South Australia in 1986-1999 were de-identified and tested for the following inherited thrombophilic polymorphisms: factor V Leiden (G1691A), prothrombin gene mutation (G20210A), methylenetetrahydrofolate reductase gene (MTHFR) C677T and A1298C, as well as compound heterozygosity for the MTHFR polymorphisms.
|
16028846 |
2005 |
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rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
Molecular analysis for thrombophilic polymorphisms documented prothrombin G20210A mutation in 3/27 (11%), homozygosity for MTHFR C677T mutation in 5/27 (18.5%, and heterozygosity for factor V Leiden mutation in 5/27 (18.5%) children.
|
11505079 |
2001 |
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rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
The genetic polymorphisms C677T and A1298C relating to the enzyme methylenetetrahydrofolate reductase (MTHFR), a clotting Factor V Leiden mutation (1691G→A substitution of Factor V Leiden), and the mutant prothrombin 20210A allele were analyzed in this study.
|
22924497 |
2012 |
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rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
The Prevalence of Factor V Leiden (G1691A) and Methylenetetrahydrofolate Reductase C677T Mutations in Sickle Cell Disease in Western India.
|
23869056 |
2015 |
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rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
We studied 24 patients with homocystinuria caused by homozygous CBS deficiency from 18 unrelated kindreds for FVL and for the 677C-->T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene and investigated their possible interaction in the risk of venous thrombosis.
|
9490685 |
1998 |
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rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
We determined whether the presence of the factor prothrombin gene G20210A variant, factor V gene G1691A mutation (factor V Leiden), and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphisms may be risk factors for vascular complications in individuals with SCD.
|
23992124 |
2013 |
|
rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
Variants of coagulation factors [factor V 1691G>A (factor V Leiden), factor V 4070A>G (factor V HR2 haplotype), factor VII Arg353Gln, factor XIII Val34Leu, beta-fibrinogen -455G>A, prothrombin 20210G>A], coagulation inhibitors [tissue factor pathway inhibitor 536C>T, thrombomodulin 127G>A], fibrinolytic factors [angiotensin converting enzyme intron 16 insertion/deletion, factor VII-activating protease 1601G>A (FSAP Marburg I), plasminogen activator inhibitor 1-675 insertion/deletion (5G/4G), tissue plasminogen activator intron h deletion/insertion], and other factors implicated in influencing susceptibility to thromboembolic diseases [apolipoprotein E2/E3/E4, glycoprotein Ia 807C>T, methylenetetrahydrofolate reductase 677C>T] were included.
|
17003923 |
2006 |
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rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
To investigate the potential perinatal effects of Factor V Leiden mutation and 5,10 methylenetetrahydrofolate reductase C677T polymorphism in preeclamptic women.
|
10877984 |
2000 |
|
rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
Three common polymorphic variants, namely Factor V Leiden (FVL), Prothrombin G20210A (PT G20210A) and Methylenetetrahydrofolate Reductase (MTHFR) C677T are candidate genes for venous thromboembolism (VTE) in pregnancy.
|
26115054 |
2015 |
|
rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
Antiphospholipid antibodies, factor V Leiden (FVL) mutation, prothrombin mutation G20210A (PTHRA20210) and mutation TT677 of methylenetetrahydrofolate reductase (MTHFR C677T) were evaluated in all patients.
|
12170404 |
2002 |
|
rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
The homozygosity of 4G in PAI-1 and MTHFR C677T genes in women with RPL, and heterozygosity of FVL, FVR2, ACE, and ApoE2 genes in both parents play crucial role in RPL and should be considered as a risk factor in RPL.
|
22047507 |
2012 |
|
rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
Homozygous mutations of the MTHFR gene (C677T) were found in six, factor-V Leiden mutation (homo- or heterozygous G1691A) in seven, and prothrombin mutation (20210A) in one patient (group 1).
|
14688517 |
2003 |
|
rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
The frequency of the thrombophilic genetic variants factor V Leiden (FVL) G1691A, prothrombin G20210A, and methylenetetrahydrofolate reductase (MTHFR) C677T in acutely symptomatic ambulatory patients with idiopathic pulmonary embolism (PE) has not been measured.
|
16574759 |
2006 |
|
rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
While factor V Leiden mutation was more common in women with pregnancy loss (25% vs. 7.6%), factor II G20210A and homozygosity for MTHFR C677T contributed to pregnancy loss only in the presence of other thrombophilia.
|
11821094 |
2002 |
|
rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
We determined if the presence of the factor V gene G1691A mutation (factor V Leiden), the prothrombin gene G20210A variant, and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism may be risk factors for vascular complications in individuals with SCD.
|
16906320 |
2006 |
|
rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
The contribution of mutations in the prothrombin (FII G20210A), methylenetetrahydrofolate reductase (C677T) genes and factor V Leiden (FVL) to the pathogenesis of arterial thrombosis remains controversial.
|
16651869 |
2006 |
|
rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
The odds ratio for stroke was not significantly increased in carriers of the prothrombin mutation (OR 1.2; 95% CI 0.1-10.7), FVL (OR 2.5; 95% CI 0.5-13.5), or the C677T mutation (OR 1.7; 95% CI 0.6-4.5).
|
10365738 |
1999 |
|
rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
To find association of angiotensin-converting enzyme (ACE) insertion/deletion (I/D), angiotensinogen (AGT) T704C, methylenetetrahydrofolate reductase (MTHFR) C677T and factor V Leiden (FVL) G1691A polymorphisms with pre-eclampsia (PE) in North Indian women.
|
21564405 |
2011 |
|
rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
The prevalence of G1691A Factor V Leiden mutation (odds ratio [OR]=0.64; 95% confidence interval [CI]: 0.04-10.5), G20210A Factor II mutation (OR=0.63; 95% CI: 0.12-3.28) and C677T MTHFR homozygous polymorphism (OR=1.13; 95% CI: 0.47-2.72) did not differ significantly among patients with or without ST.
|
22665071 |
2012 |
|
rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
No significant increased risk for venous thrombosis was found when MTHFR 1298 A --> C was coinherited with FVL (OR 2.85, 95% CI 0.88-9.23), FII 20210 G --> A (OR 7.19, 95% CI 0.87-59.4) or MTHFR 677 C --> T (OR 1.44, 95% CI 0.71-2.92).
|
10233437 |
1999 |
|
rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
This pilot study examined Factor V Leiden (R506Q), prothrombin (20210G-->A), thrombomodulin (A455V) and MTHFR (677C-->T) in 100 Zulu-speaking black South African women with placental abruption and 217 controls.
|
12066950 |
2002 |
|
rs1217691063
|
|
Factor V Leiden mutation
|
|
0.100 |
GeneticVariation
|
BEFREE |
We analysed the prevalence of the most common hereditary thrombophilia (hTP) - factor V Leiden (FVL) mutation, prothrombin 20210 G>A substitution (PT) - and the 677 C>T replacement in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene in Caucasian patients with a history of two and more consecutive recurrent miscarriages (RMs) as compared to healthy controls with an identical ethnic background and at least one live birth.
|
23795816 |
2013 |