|
rs1801157
|
|
HIV-1 infection
|
|
0.010 |
GeneticVariation
|
BEFREE |
To identify additional alleles that may influence HIV-1 infection and progression to AIDS, nine SNPs (including rs1801157) spanning 20.2 kb in and around the SDF-1 gene were genotyped in over 3000 African American (AA) and European American (EA) participants enrolled in five longitudinal HIV-1/AIDS natural cohort studies.
|
16177829 |
2005 |
|
rs1801157
|
|
Neoplasm Metastasis
|
|
0.050 |
GeneticVariation
|
BEFREE |
We were also unable to find a correlation between rs1801157 and different prognostic markers such as metastasis development or disease-free survival time.
|
17982648 |
2007 |
|
rs1801157
|
|
Malignant neoplasm of colon and/or rectum
|
|
0.020 |
GeneticVariation
|
BEFREE |
The epidemiologic data involving CXCL12 rs1801157 in colorectal cancer risk are discussed.
|
17982648 |
2007 |
|
rs1801157
|
|
Colorectal Carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
The epidemiologic data involving CXCL12 rs1801157 in colorectal cancer risk are discussed.
|
17982648 |
2007 |
|
rs1801157
|
|
Colon Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Recently, a G>A functional transition mapping the 3' untranslated region of the CXCL12 gene (rs1801157) has been found to be under-represented among rectal cancer patients when compared to colon cancer patients from a Swedish series.
|
17982648 |
2007 |
|
rs1801157
|
|
Malignant tumor of colon
|
|
0.010 |
GeneticVariation
|
BEFREE |
Recently, a G>A functional transition mapping the 3' untranslated region of the CXCL12 gene (rs1801157) has been found to be under-represented among rectal cancer patients when compared to colon cancer patients from a Swedish series.
|
17982648 |
2007 |
|
rs1801157
|
|
Breast Carcinoma
|
|
0.060 |
GeneticVariation
|
BEFREE |
Similarly, the SNP barcode of rs12812942-rs2228014-rs3025039 (CD4-CXCR4-VEGF) and rs12812942-rs3136685-rs2228014-rs1801157 (CD4- CCR7-CXCR4-CXCL12) with specific genotype patterns (AT-CC-CC and AT-AG-CC-GG) among three and four combinational SNPs were significantly low in breast cancer occurrence.
|
19196101 |
2009 |
|
rs1801157
|
|
Malignant neoplasm of breast
|
|
0.060 |
GeneticVariation
|
BEFREE |
CXCL12 rs1801157 polymorphism in patients with breast cancer, Hodgkin's lymphoma, and non-Hodgkin's lymphoma.
|
19927352 |
2009 |
|
rs1801157
|
|
Breast Carcinoma
|
|
0.060 |
GeneticVariation
|
BEFREE |
CXCL12 rs1801157 polymorphism in patients with breast cancer, Hodgkin's lymphoma, and non-Hodgkin's lymphoma.
|
19927352 |
2009 |
|
rs1801157
|
|
Malignant neoplasm of breast
|
|
0.060 |
GeneticVariation
|
BEFREE |
Similarly, the SNP barcode of rs12812942-rs2228014-rs3025039 (CD4-CXCR4-VEGF) and rs12812942-rs3136685-rs2228014-rs1801157 (CD4- CCR7-CXCR4-CXCL12) with specific genotype patterns (AT-CC-CC and AT-AG-CC-GG) among three and four combinational SNPs were significantly low in breast cancer occurrence.
|
19196101 |
2009 |
|
rs1801157
|
|
Neoplasm Metastasis
|
|
0.050 |
GeneticVariation
|
BEFREE |
The single-nucleotide polymorphism (SNP) rs1801157 (previously known as CXCL12-A/ stromal cell-derived factor-1 (SDF1)-3'A) in CXCL12/SDF1 gene was assessed in breast cancer, Hodgkin's lymphoma (HL), and non-Hodgkin's lymphoma (NHL), since the chemokine CXCL12, previously known as SDF1, and its receptor CXCR4 regulate leukocyte trafficking and many essential biological processes, including tumor growth, angiogenesis, and metastasis of different types of tumors.
|
19927352 |
2009 |
|
rs1801157
|
|
Liver carcinoma
|
|
0.020 |
GeneticVariation
|
BEFREE |
Polymerase chain reaction-restriction fragment length polymorphism was used to measure SDF-1 (rs1801157) and CXCR4 (rs2228014) gene polymorphisms in 311 healthy controls and 102 patients with HCC.
|
19327121 |
2009 |
|
rs1801157
|
|
Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
The single-nucleotide polymorphism (SNP) rs1801157 (previously known as CXCL12-A/ stromal cell-derived factor-1 (SDF1)-3'A) in CXCL12/SDF1 gene was assessed in breast cancer, Hodgkin's lymphoma (HL), and non-Hodgkin's lymphoma (NHL), since the chemokine CXCL12, previously known as SDF1, and its receptor CXCR4 regulate leukocyte trafficking and many essential biological processes, including tumor growth, angiogenesis, and metastasis of different types of tumors.
|
19927352 |
2009 |
|
rs1801157
|
|
Lymphoma, Non-Hodgkin
|
|
0.020 |
GeneticVariation
|
BEFREE |
However, this study suggests that CXCL12 rs1801157 polymorphism may have important implications in the pathogenesis of NHL.
|
19927352 |
2009 |
|
rs1801157
|
|
Childhood Hodgkin Lymphoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The single-nucleotide polymorphism (SNP) rs1801157 (previously known as CXCL12-A/ stromal cell-derived factor-1 (SDF1)-3'A) in CXCL12/SDF1 gene was assessed in breast cancer, Hodgkin's lymphoma (HL), and non-Hodgkin's lymphoma (NHL), since the chemokine CXCL12, previously known as SDF1, and its receptor CXCR4 regulate leukocyte trafficking and many essential biological processes, including tumor growth, angiogenesis, and metastasis of different types of tumors.
|
19927352 |
2009 |
|
rs1801157
|
|
Lymphoma, Non-Hodgkin, Familial
|
|
0.010 |
GeneticVariation
|
BEFREE |
CXCL12 rs1801157 polymorphism in patients with breast cancer, Hodgkin's lymphoma, and non-Hodgkin's lymphoma.
|
19927352 |
2009 |
|
rs1801157
|
|
Adult Non-Hodgkin Lymphoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
CXCL12 rs1801157 polymorphism in patients with breast cancer, Hodgkin's lymphoma, and non-Hodgkin's lymphoma.
|
19927352 |
2009 |
|
rs1801157
|
|
Adult Hodgkin Lymphoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The single-nucleotide polymorphism (SNP) rs1801157 (previously known as CXCL12-A/ stromal cell-derived factor-1 (SDF1)-3'A) in CXCL12/SDF1 gene was assessed in breast cancer, Hodgkin's lymphoma (HL), and non-Hodgkin's lymphoma (NHL), since the chemokine CXCL12, previously known as SDF1, and its receptor CXCR4 regulate leukocyte trafficking and many essential biological processes, including tumor growth, angiogenesis, and metastasis of different types of tumors.
|
19927352 |
2009 |
|
rs1801157
|
|
Hodgkin Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
The single-nucleotide polymorphism (SNP) rs1801157 (previously known as CXCL12-A/ stromal cell-derived factor-1 (SDF1)-3'A) in CXCL12/SDF1 gene was assessed in breast cancer, Hodgkin's lymphoma (HL), and non-Hodgkin's lymphoma (NHL), since the chemokine CXCL12, previously known as SDF1, and its receptor CXCR4 regulate leukocyte trafficking and many essential biological processes, including tumor growth, angiogenesis, and metastasis of different types of tumors.
|
19927352 |
2009 |
|
rs1801157
|
|
Childhood Non-Hodgkin Lymphoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
CXCL12 rs1801157 polymorphism in patients with breast cancer, Hodgkin's lymphoma, and non-Hodgkin's lymphoma.
|
19927352 |
2009 |
|
rs1801157
|
|
Breast Carcinoma
|
|
0.060 |
GeneticVariation
|
BEFREE |
The CXCL12-3' G801A transition (rs1801157) has been associated with the incidence of breast cancer.
|
20406099 |
2010 |
|
rs1801157
|
|
Malignant neoplasm of breast
|
|
0.060 |
GeneticVariation
|
BEFREE |
The CXCL12-3' G801A transition (rs1801157) has been associated with the incidence of breast cancer.
|
20406099 |
2010 |
|
rs1801157
|
|
Myocardial Infarction
|
|
0.030 |
GeneticVariation
|
BEFREE |
This study was aimed to investigate whether the SDF1-3'A polymorphism (rs1801157) is associated to myocardial infarction (MI) in a sample of Chinese Han population.
|
19821058 |
2010 |
|
rs1801157
|
|
Malignant neoplasm of breast
|
|
0.060 |
GeneticVariation
|
BEFREE |
However a significant difference was observed when CXCL12 mRNA relative expression was analyzed in breast cancer patients in accordance to the presence or absence of the CXCL12 rs1801157 allele A. Allele A breast cancer patients presented a mRNA CXCL12 expression about 2.1-fold smaller than GG breast cancer patients.
|
21592819 |
2011 |
|
rs1801157
|
|
Breast Carcinoma
|
|
0.060 |
GeneticVariation
|
BEFREE |
However a significant difference was observed when CXCL12 mRNA relative expression was analyzed in breast cancer patients in accordance to the presence or absence of the CXCL12 rs1801157 allele A. Allele A breast cancer patients presented a mRNA CXCL12 expression about 2.1-fold smaller than GG breast cancer patients.
|
21592819 |
2011 |