|
rs1801157
|
|
HIV Infections
|
|
0.010 |
GeneticVariation
|
BEFREE |
After adjusting by age, route of HIV infection, length of infection before cART and viral hepatitis coinfection, CCR2 rs1799864-AG genotype was significantly associated with INR status (OR [95% CI]: 1.80 [1.04-3.11]; p = 0.04), and CXCL12 rs1801157-TT genotype showed a trend (OR [95% CI]: 2.47 [0.96-6.35]; p = 0.06).
|
30921390 |
2019 |
|
rs1801157
|
|
Coinfection
|
|
0.010 |
GeneticVariation
|
BEFREE |
After adjusting by age, route of HIV infection, length of infection before cART and viral hepatitis coinfection, CCR2 rs1799864-AG genotype was significantly associated with INR status (OR [95% CI]: 1.80 [1.04-3.11]; p = 0.04), and CXCL12 rs1801157-TT genotype showed a trend (OR [95% CI]: 2.47 [0.96-6.35]; p = 0.06).
|
30921390 |
2019 |
|
rs1801157
|
|
Human papilloma virus infection
|
|
0.010 |
GeneticVariation
|
BEFREE |
In the present study, we demonstrated that CXCL12 rs1801157 is independently associated with HPV infection and exerts influence in HSIL development, suggesting it as a promising susceptibility biomarker for HPV infection and lesions development.
|
30227860 |
2018 |
|
rs1801157
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.010 |
GeneticVariation
|
BEFREE |
Conclusion Both dominant and additive models in both KCNJ11 (E23K, rs5219) and SDF-1β (G801A, rs1801157) genetic polymorphisms are significantly associated with type 2 diabetes.
|
29893194 |
2018 |
|
rs1801157
|
|
Triple Negative Breast Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
The present study analyzed genetic polymorphisms in CXCL12 (rs1801157, G > A) and CXCR4 (rs2228014, C > T) and CXCR4 immunostaining in tumor tissues from patients with triple negative breast cancer (TNBC) aiming to evaluate their possible role in its' susceptibility and prognosis.
|
29926386 |
2018 |
|
rs1801157
|
|
Triple-Negative Breast Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The present study analyzed genetic polymorphisms in CXCL12 (rs1801157, G > A) and CXCR4 (rs2228014, C > T) and CXCR4 immunostaining in tumor tissues from patients with triple negative breast cancer (TNBC) aiming to evaluate their possible role in its' susceptibility and prognosis.
|
29926386 |
2018 |
|
rs1801157
|
|
Diabetic foot ulcer
|
|
0.010 |
GeneticVariation
|
BEFREE |
The Interleukin (IL)-6 (-174G > C/rs1800795), Tumor Necrosis Factor (TNF)-α (-308G > A/rs1800629) and (-238G > A/rs361525) and Stromal cell Derived Factor (SDF)-1 (+801G > A/rs1801157) are well characterized single nucleotide polymorphisms (SNPs) which were previously shown to be associated with Diabetic Foot Ulcer (DFU).
|
30009916 |
2018 |
|
rs1801157
|
|
Hematologic Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
Several recent studies have shown that <i>SDF1</i>-3'A polymorphism (rs1801157) is associated with susceptibility to hematological malignancy, but published studies' results are disputed.
|
28352190 |
2017 |
|
rs1801157
|
|
Lupus Erythematosus, Systemic
|
|
0.010 |
GeneticVariation
|
BEFREE |
<i>SDF-1</i> rs1801157 polymorphism may not influence the risk of SLE.
|
29088886 |
2017 |
|
rs1801157
|
|
Malignant neoplasm of lung
|
|
0.010 |
GeneticVariation
|
BEFREE |
In summary, this study suggested that the SDF-1 rs1801157 polymorphism may serve as a risk factor for cancer development among Asians, especially an increased risk of urologic and lung cancers.
|
27265091 |
2016 |
|
rs1801157
|
|
Childhood Leukemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
This study aimed to determine the associations between the polymorphisms located on the SDF-1 (rs1801157, G>A) and CXCR4 (rs2228014, C>T) encoding genes and susceptibility and leukemia cell dissemination in AML.
|
27154815 |
2016 |
|
rs1801157
|
|
Chronic Lymphocytic Leukemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
In conclusion, data from this study indicate that the CXCL12 rs1801157 G > A polymorphism may affect CLL development, disease progression as well as response to treatment.
|
27173875 |
2016 |
|
rs1801157
|
|
Cancer of Urinary Tract
|
|
0.010 |
GeneticVariation
|
BEFREE |
Moreover, we confirmed that the SDF-1 rs1801157 gene polymorphism was only associated with lung and urologic cancer risk.
|
27265091 |
2016 |
|
rs1801157
|
|
Leukemia, Myelocytic, Acute
|
|
0.010 |
GeneticVariation
|
BEFREE |
Genotype CT of rs2228014 appeared to correlate with AML risk, but played no role in leukemia cells invading the bloodstream, while rs1801157 and the two combined SNPs were not associated with either increased AML risk or extramedullary leukemia-cell dissemination.
|
27154815 |
2016 |
|
rs1801157
|
|
leukemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
This study aimed to determine the associations between the polymorphisms located on the SDF-1 (rs1801157, G>A) and CXCR4 (rs2228014, C>T) encoding genes and susceptibility and leukemia cell dissemination in AML.
|
27154815 |
2016 |
|
rs1801157
|
|
Coronary Arteriosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Lack of an Association between the SDF-1 rs1801157 Polymorphism and Coronary Heart Disease: A Meta-Analysis.
|
26133117 |
2015 |
|
rs1801157
|
|
Complications of Diabetes Mellitus
|
|
0.010 |
GeneticVariation
|
BEFREE |
The IL-6 -174G/C (rs1800795), TNF-α -308G/A (rs1800629) and -238G/A (rs361525) and SDF-1 801G/A (rs1801157) are well characterized SNPs which have previously been linked to various diabetic complications.
|
25839939 |
2015 |
|
rs1801157
|
|
Childhood Acute Lymphoblastic Leukemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
Genetic polymorphisms in the 3'UTR region of the CXCL12 (rs1801157) and TP53 codon 72 (rs1042522) genes may contribute to susceptibility to childhood ALL because they affect some important processes, such as metastasis regulation and tumor suppression.
|
23653000 |
2013 |
|
rs1801157
|
|
Acute lymphocytic leukemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
Genetic polymorphisms in the 3'UTR region of the CXCL12 (rs1801157) and TP53 codon 72 (rs1042522) genes may contribute to susceptibility to childhood ALL because they affect some important processes, such as metastasis regulation and tumor suppression.
|
23653000 |
2013 |
|
rs1801157
|
|
Adult Acute Lymphocytic Leukemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
Genetic polymorphisms in the 3'UTR region of the CXCL12 (rs1801157) and TP53 codon 72 (rs1042522) genes may contribute to susceptibility to childhood ALL because they affect some important processes, such as metastasis regulation and tumor suppression.
|
23653000 |
2013 |
|
rs1801157
|
|
Infections specific to perinatal period
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results indicate that the rs1801157 SNP does not influence perinatal infection, but impacts disease progression.
|
22962615 |
2012 |
|
rs1801157
|
|
Ovarian Failure, Premature
|
|
0.010 |
GeneticVariation
|
BEFREE |
The A allele of CXCL12 polymorphism rs1801157 is a possible risk factor for developing POF.
|
21296802 |
2011 |
|
rs1801157
|
|
SVEINSSON CHORIORETINAL ATROPHY
|
|
0.010 |
GeneticVariation
|
BEFREE |
Expression of the CXCL12 (SNP rs1801157) polymorphisms GA/AA significantly correlated with distant metastasis (P=0.026), but not with prognosis.
|
21584490 |
2011 |
|
rs1801157
|
|
Premature Menopause
|
|
0.010 |
GeneticVariation
|
BEFREE |
The A allele of CXCL12 polymorphism rs1801157 is a possible risk factor for developing POF.
|
21296802 |
2011 |
|
rs1801157
|
|
Childhood Hodgkin Lymphoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The single-nucleotide polymorphism (SNP) rs1801157 (previously known as CXCL12-A/ stromal cell-derived factor-1 (SDF1)-3'A) in CXCL12/SDF1 gene was assessed in breast cancer, Hodgkin's lymphoma (HL), and non-Hodgkin's lymphoma (NHL), since the chemokine CXCL12, previously known as SDF1, and its receptor CXCR4 regulate leukocyte trafficking and many essential biological processes, including tumor growth, angiogenesis, and metastasis of different types of tumors.
|
19927352 |
2009 |