Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10456057
rs10456057
HLA-B ; USP8P1
CUI: C1836232
Disease: ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO
ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO 		0.700 GeneticVariation GWASDB The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. 21051598

2010
dbSNP: rs10456057
rs10456057
HLA-B ; USP8P1
CUI: C1836231
Disease: HIV-1, RESISTANCE TO
HIV-1, RESISTANCE TO 		0.700 GeneticVariation GWASDB The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. 21051598

2010
dbSNP: rs10456057
rs10456057
HLA-B ; USP8P1
CUI: C1836230
Disease: HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO
HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO 		0.700 GeneticVariation GWASDB The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. 21051598

2010
dbSNP: rs10456057
rs10456057
HLA-B ; USP8P1
CUI: C1836233
Disease: AIDS, PROGRESSION TO
AIDS, PROGRESSION TO 		0.700 GeneticVariation GWASDB The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. 21051598

2010
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.810 GeneticVariation GWASDB A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. 20953190

2010
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.810 GeneticVariation GWASCAT A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. 20953190

2010
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C0033860
Disease: Psoriasis
Psoriasis 		T 0.810 GeneticVariation GWASCAT Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. 26626624

2015
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.810 GeneticVariation BEFREE We investigated, in 461 psoriatic patients and 454 healthy controls, the associations with psoriasis of four single-nucleotide polymorphisms (SNPs) from the psoriasis susceptibility 1 (PSORS1) interval: rs1062470 (PSORS1C1/CDSN), rs887466 (PSORS1C3), rs2894207 and rs10484554 (LOC105375015). 29589160

2018
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C0033860
Disease: Psoriasis
Psoriasis 		T 0.810 GeneticVariation GWASCAT A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci. 18369459

2008
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C0033860
Disease: Psoriasis
Psoriasis 		T 0.810 GeneticVariation GWASDB A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci. 18369459

2008
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome 		T 0.800 GeneticVariation GWASCAT Genomewide association study of an AIDS-nonprogression cohort emphasizes the role played by HLA genes (ANRS Genomewide Association Study 02). 19115949

2009
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome 		T 0.800 GeneticVariation GWASDB Genomewide association study of an AIDS-nonprogression cohort emphasizes the role played by HLA genes (ANRS Genomewide Association Study 02). 19115949

2009
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.710 GeneticVariation GWASDB REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis. 19503088

2009
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.710 GeneticVariation BEFREE When the HLA-C rs10484554 CC homozygote genotype was used as the reference group, the TT/CT genotypes were associated with a significantly decreased risk for RA (adjusted OR = 0.72, 95% CI = 0.52-0.99, p = 0.044). 24566686

2014
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C1836231
Disease: HIV-1, RESISTANCE TO
HIV-1, RESISTANCE TO 		0.700 GeneticVariation GWASDB The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. 21051598

2010
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C1836231
Disease: HIV-1, RESISTANCE TO
HIV-1, RESISTANCE TO 		0.700 GeneticVariation GWASDB Common genetic variation and the control of HIV-1 in humans. 20041166

2009
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C1836232
Disease: ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO
ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO 		0.700 GeneticVariation GWASDB Common genetic variation and the control of HIV-1 in humans. 20041166

2009
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C0042900
Disease: Vitiligo
Vitiligo 		0.700 GeneticVariation GWASDB Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC. 20526339

2010
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C1836232
Disease: ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO
ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO 		0.700 GeneticVariation GWASDB The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. 21051598

2010
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C1836233
Disease: AIDS, PROGRESSION TO
AIDS, PROGRESSION TO 		0.700 GeneticVariation GWASDB The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. 21051598

2010
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C1836230
Disease: HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO
HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO 		0.700 GeneticVariation GWASDB The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. 21051598

2010
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C1836233
Disease: AIDS, PROGRESSION TO
AIDS, PROGRESSION TO 		0.700 GeneticVariation GWASDB Common genetic variation and the control of HIV-1 in humans. 20041166

2009
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C1836230
Disease: HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO
HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO 		0.700 GeneticVariation GWASDB Common genetic variation and the control of HIV-1 in humans. 20041166

2009
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C1519176
Disease: Salivary Gland Pleomorphic Adenoma
Salivary Gland Pleomorphic Adenoma 		0.010 GeneticVariation BEFREE The most highly associated SNP was rs10484554, which lies 34.7 kb upstream from HLA-C (P = 7.8x10(-11), GWA scan; P = 1.8x10(-30), replication; P = 1.8x10(-39), combined; U.K. PSA: P = 6.9x10(-11)). 18369459

2008
dbSNP: rs10484554
rs10484554
HLA-B ; LOC112267902
CUI: C0019693
Disease: HIV Infections
HIV Infections 		0.010 GeneticVariation BEFREE This variant is associated with low viral set point following HIV infection and its effect is independent of rs10484554. 18369459

2008