|
rs28897759
|
|
Malignant neoplasm of breast
|
|
0.810 |
GeneticVariation
|
UNIPROT |
|
|
|
|
rs28897759
|
|
Malignant neoplasm of breast
|
T |
0.810 |
GeneticVariation
|
CLINVAR |
|
|
|
|
rs55770810
|
|
Malignant neoplasm of breast
|
|
0.810 |
GeneticVariation
|
UNIPROT |
Summaries for patients. Assessing the genetic risk for BRCA-related breast or ovarian cancer in women: recommendations from the U.S. Preventive Services Task Force.
|
24366402 |
2014 |
|
rs55770810
|
|
Malignant neoplasm of breast
|
|
0.810 |
GeneticVariation
|
UNIPROT |
Risk assessment, genetic counseling, and genetic testing for BRCA-related cancer in women: U.S. Preventive Services Task Force recommendation statement.
|
24366376 |
2014 |
|
rs55770810
|
|
Malignant neoplasm of breast
|
|
0.810 |
GeneticVariation
|
UNIPROT |
The emerging landscape of breast cancer susceptibility.
|
18163131 |
2008 |
|
rs55770810
|
|
Malignant neoplasm of breast
|
|
0.810 |
GeneticVariation
|
UNIPROT |
Risk assessment and genetic counseling for hereditary breast and ovarian cancer: recommendations of the National Society of Genetic Counselors.
|
17508274 |
2007 |
|
rs55770810
|
|
Malignant neoplasm of breast
|
|
0.810 |
GeneticVariation
|
UNIPROT |
Genetic cancer risk assessment and counseling: recommendations of the national society of genetic counselors.
|
15604628 |
2004 |
|
rs55770810
|
|
Malignant neoplasm of breast
|
A |
0.810 |
CausalMutation
|
CLINVAR |
|
|
|
|
rs10941679
|
|
Malignant neoplasm of breast
|
G |
0.800 |
GeneticVariation
|
GWASDB |
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
|
23535729 |
2013 |
|
rs121913279
|
|
Malignant neoplasm of breast
|
|
0.800 |
GeneticVariation
|
UNIPROT |
PIK3CA mutation and histological type in breast carcinoma: high frequency of mutations in lobular carcinoma.
|
16353168 |
2006 |
|
rs1219648
|
|
Malignant neoplasm of breast
|
G |
0.800 |
GeneticVariation
|
GWASDB |
A combined analysis of genome-wide association studies in breast cancer.
|
20872241 |
2011 |
|
rs1219648
|
|
Malignant neoplasm of breast
|
|
0.800 |
GeneticVariation
|
GWASDB |
Novel breast cancer susceptibility locus at 9q31.2: results of a genome-wide association study.
|
21263130 |
2011 |
|
rs1219648
|
|
Malignant neoplasm of breast
|
G |
0.800 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer.
|
17529973 |
2007 |
|
rs13281615
|
|
Malignant neoplasm of breast
|
G |
0.800 |
GeneticVariation
|
GWASDB |
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
|
23535729 |
2013 |
|
rs13281615
|
|
Malignant neoplasm of breast
|
T |
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies novel breast cancer susceptibility loci.
|
17529967 |
2007 |
|
rs13387042
|
|
Malignant neoplasm of breast
|
A |
0.800 |
GeneticVariation
|
GWASDB |
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
|
23535729 |
2013 |
|
rs13387042
|
|
Malignant neoplasm of breast
|
A |
0.800 |
GeneticVariation
|
GWASDB |
Novel breast cancer susceptibility locus at 9q31.2: results of a genome-wide association study.
|
21263130 |
2011 |
|
rs13387042
|
|
Malignant neoplasm of breast
|
A |
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies five new breast cancer susceptibility loci.
|
20453838 |
2010 |
|
rs13387042
|
|
Malignant neoplasm of breast
|
A |
0.800 |
GeneticVariation
|
GWASDB |
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1).
|
19330030 |
2009 |
|
rs13387042
|
|
Malignant neoplasm of breast
|
A |
0.800 |
GeneticVariation
|
GWASDB |
At present, no genes have been identified in the linkage disequilibrium block containing rs13387042. rs3803662 is near the 5' end of TNRC9 , a high mobility group chromatin-associated protein whose expression is implicated in breast cancer metastasis to bone.
|
17529974 |
2007 |
|
rs17879961
|
|
Malignant neoplasm of breast
|
G |
0.800 |
GeneticVariation
|
CLINVAR |
CHEK2 mutations and the risk of papillary thyroid cancer.
|
25583358 |
2015 |
|
rs17879961
|
|
Malignant neoplasm of breast
|
G |
0.800 |
GeneticVariation
|
CLINVAR |
Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.
|
24880342 |
2014 |
|
rs17879961
|
|
Malignant neoplasm of breast
|
G |
0.800 |
GeneticVariation
|
CLINVAR |
In total, 26,336 cases and 44,219 controls from 18 case-control studies were used in this meta-analysis, and significant associations of the CHEK2 I157T variant with cancer susceptibility were found (OR, 1.39; 95% CI, 1.19-1.63; p<0.0001), breast cancer (OR=1.58, 95% CI=1.42-1.75, p<0.00001) and colorectal cancer (OR=1.67, 95% CI=1.24-2.26, p=0.0008).
|
23713947 |
2013 |
|
rs17879961
|
|
Malignant neoplasm of breast
|
G |
0.800 |
GeneticVariation
|
CLINVAR |
BRCA1, TP53, and CHEK2 germline mutations in uterine serous carcinoma.
|
22811390 |
2013 |
|
rs17879961
|
|
Malignant neoplasm of breast
|
G |
0.800 |
GeneticVariation
|
CLINVAR |
The risk of gastric cancer in carriers of CHEK2 mutations.
|
23296741 |
2013 |