|
rs11868035
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
We followed up 212 randomly selected, nonobese, nondiabetic, insulin-sensitive participants in a population-based study without NAFLD or metabolic syndrome at baseline who were characterized for the common SREBF-1c gene rs11868035 A/G polymorphism, dietary habits, physical activity, adipokine profile, C-reactive protein (CRP), and circulating markers of endothelial dysfunction.
|
23985808 |
2013 |
|
rs1191926239
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
The IL6 -174G>C and CD14 -260C>T polymorphisms are likely to be associated with a pro-atherogenic profile but not with increased inflammatory markers and endothelial dysfunction in young AMI patients.
|
23135962 |
2013 |
|
rs1395198370
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of this study was to search for an association between V249I and T280M polymorphisms of CX3CR1, preeclampsia and endothelial dysfunction.
|
19587779 |
2009 |
|
rs1800629
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
In this regard, besides a strong association between the HLA-DRB1∗04 shared epitope alleles and both endothelial dysfunction, an early step in the atherosclerotic process, and clinically evident CV disease, other polymorphisms belonging to genes implicated in inflammatory and metabolic pathways, located inside and outside the HLA region, such as the 308 variant (G > A, rs1800629) of the TNFA locus, the rs1801131 polymorphism (A > C; position + 1298) of the MTHFR locus, or a deletion of 32 base pairs on the CCR5 gene, seem to be associated with the risk of CV disease in patients with RA.
|
22927710 |
2012 |
|
rs2295490
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
The relatively common TRIB3 Q84R polymorphism (rs2295490) has been associated with abnormal insulin signaling, endothelial dysfunction, insulin resistance, and pro-atherogenic phenotypes.
|
26253791 |
2015 |
|
rs3732378
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of this study was to search for an association between V249I and T280M polymorphisms of CX3CR1, preeclampsia and endothelial dysfunction.
|
19587779 |
2009 |
|
rs375752214
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
An increasing body of evidence suggests that different genetic factors, such as angiotensin-converting enzyme (ACE) I/D, angiotensin II type-1 receptor (AT1R) A1166C, methylenetetrahydrofolate reductase (MTHFR) C677T and ENOS G894T variants are associated with an endothelial dysfunction (ED).
|
17504188 |
2007 |
|
rs3848403
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of our study was to evaluate an association of FN3K (rs1056534, rs3848403) and GLO1 rs4746 polymorphisms with parameters of endothelial dysfunction and soluble receptor for AGEs (sRAGE) in 595 diabetic and non-diabetic subjects.
|
24908234 |
2014 |
|
rs4746
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of our study was to evaluate an association of FN3K (rs1056534, rs3848403) and GLO1 rs4746 polymorphisms with parameters of endothelial dysfunction and soluble receptor for AGEs (sRAGE) in 595 diabetic and non-diabetic subjects.
|
24908234 |
2014 |
|
rs4961
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
Since inflammatory mechanisms may be involved in pathophysiology of hypertension and in endothelial dysfunction and atherosclerosis through reactive oxygen species, the baseline urinary excretion of inflammatory and oxidative stress markers in a subgroup of adolescents stratified according to <i>ADD1</i>(alpha adducin) rs4961 genotypes was assessed.
|
31760884 |
2020 |
|
rs5443
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of the study was to examine the association between the G protein β3 subunit C825T polymorphism, associated with cardiovascular risk factors like hypertension (HT) and obesity and microalbuminuria (MA), reflecting the endothelial dysfunction in the atherosclerotic process.
|
20577224 |
2010 |
|
rs57920071
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
These data suggest that farnesylated p.R482W-prelamin-A accumulation at the nuclear envelope is a toxic event, leading to cellular oxidative stress and endothelial dysfunction.
|
23846499 |
2013 |
|
rs599839
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results confirm an association of the rs599839 polymorphism with endothelial dysfunction in RA.
|
22380622 |
2012 |
|
rs753482
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
Measures of glucose tolerance, insulin sensitivity, markers of endothelial dysfunction, forearm vasodilation, and adipokine levels were determined and associated to the frequency of two single-nucleotide polymorphisms of NOS3, i.e., Glu298Asp (rs1799983, G/T) and rs753482 (intron 18 A/C).
|
18349107 |
2008 |
|
rs754390004
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of this study was to search for an association between V249I and T280M polymorphisms of CX3CR1, preeclampsia and endothelial dysfunction.
|
19587779 |
2009 |
|
rs772155434
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
The purpose of this study was to determine whether the gene variant in the HBD of ECSOD (ECSOD(R213G)) protects against endothelial dysfunction in a model of inflammation.
|
17717013 |
2007 |
|
rs910042982
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
Endothelial dysfunction in angiotensin II-treated E-V290M vasopressin-exposed offspring was attenuated by tempol, an effect which was more prominent in male offspring.
|
31104564 |
2019 |
|
rs9818870
|
|
Endothelial dysfunction
|
|
0.010 |
GeneticVariation
|
BEFREE |
The augmented endothelium-dependent vasodilation of the forearm resistance vasculature does not support the presence of endothelial dysfunction in young SNP carriers and indicates that other mechanisms are responsible for the strong association between coronary artery diseases and the rs9818870 polymorphism, located on 3q22.3.
|
26284284 |
2015 |