DisGeNET - a database of gene-disease associations

Source: GWASCAT

Disease: Bilirubin measurement ×

Gene: UGT1A3 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs4477910

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.700

GeneticVariation

GWASCAT

Phenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols.

25884002

2015

dbSNP:

rs4663969

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Phenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols.

25884002

2015

dbSNP:

rs6431630

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.

29403010

2018

dbSNP:

rs6714634

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3 ; LOC100286922

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs6742078

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genome-wide association meta-analysis for total serum bilirubin levels.

19414484

2009

dbSNP:

rs6742078

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

23371916

2013

dbSNP:

rs6742078

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genome-wide association of serum bilirubin levels in Korean population.

20639394

2010

dbSNP:

rs6742078

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs6747843

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3 ; LOC100286922

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.700

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs75520741

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.700

GeneticVariation

GWASCAT

Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.

29403010

2018

dbSNP:

rs7564935

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa.

31675503

2019

dbSNP:

rs7604115

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs8330

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3 ; MROH2A

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.

29403010

2018

dbSNP:

rs887829

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

23642732

2013

dbSNP:

rs887829

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs887829

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.

22558097

2012

dbSNP:

rs887829

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Taking advantage of the lower LD and shorter haplotypes in African-ancestry populations, we identified rs887829 as a more refined proxy for the causative variant influencing bilirubin levels.

22085899

2012

dbSNP:

rs887829

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Phenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols.

25884002

2015

dbSNP:

rs887829

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.

19419973

2009

dbSNP:

rs929596

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.

26148204

2015

dbSNP:

rs929596

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Phenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols.

25884002

2015

dbSNP:

rs929596

UGT1A10 ; UGT1A8 ; UGT1A7 ; UGT1A6 ; UGT1A5 ; UGT1A9 ; UGT1A4 ; UGT1A1 ; UGT1A3

CUI:	C0344395
Disease:	Bilirubin measurement

Bilirubin measurement

0.800

GeneticVariation

GWASCAT

Genome-Wide Association Study (GWAS) on Bilirubin Concentrations in Subjects with Metabolic Syndrome: Sex-Specific GWAS Analysis and Gene-Diet Interactions in a Mediterranean Population.

30621171

2019