Source: GWASCAT

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7216389
rs7216389
GSDMB
CUI: C0004096
Disease: Asthma
Asthma 		T 0.900 GeneticVariation GWASCAT Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. 17611496

2007
dbSNP: rs2305480
rs2305480
GSDMB
CUI: C0004096
Disease: Asthma
Asthma 		G 0.860 GeneticVariation GWASCAT A large-scale, consortium-based genomewide association study of asthma. 20860503

2010
dbSNP: rs1295686
rs1295686
IL13 ; TH2LCRR
CUI: C0004096
Disease: Asthma
Asthma 		T 0.840 GeneticVariation GWASCAT A large-scale, consortium-based genomewide association study of asthma. 20860503

2010
dbSNP: rs1342326
rs1342326
CUI: C0004096
Disease: Asthma
Asthma 		C 0.840 GeneticVariation GWASCAT We observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3×10(−9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7×10(−14)); rs1342326 on chromosome 9, flanking IL33 (P=9×10(−10)); rs744910 on chromosome 15 in SMAD3 (P=4×10(−9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1×10(−8)). 20860503

2010
dbSNP: rs1837253
rs1837253
CUI: C0004096
Disease: Asthma
Asthma 		C 0.840 GeneticVariation GWASCAT Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study. 30552067

2019
dbSNP: rs1837253
rs1837253
CUI: C0004096
Disease: Asthma
Asthma 		C 0.840 GeneticVariation GWASCAT Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. 31619474

2019
dbSNP: rs1837253
rs1837253
CUI: C0004096
Disease: Asthma
Asthma 		C 0.840 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738

2019
dbSNP: rs1837253
rs1837253
CUI: C0004096
Disease: Asthma
Asthma 		0.840 GeneticVariation GWASCAT A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases. 29785011

2018
dbSNP: rs1837253
rs1837253
CUI: C0004096
Disease: Asthma
Asthma 		0.840 GeneticVariation GWASCAT Identification of Four Novel Loci in Asthma in European American and African American Populations. 27611488

2017
dbSNP: rs1837253
rs1837253
CUI: C0004096
Disease: Asthma
Asthma 		0.840 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965

2016
dbSNP: rs1837253
rs1837253
CUI: C0004096
Disease: Asthma
Asthma 		C 0.840 GeneticVariation GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013

2014
dbSNP: rs1837253
rs1837253
CUI: C0004096
Disease: Asthma
Asthma 		0.840 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549

2011
dbSNP: rs1837253
rs1837253
CUI: C0004096
Disease: Asthma
Asthma 		C 0.840 GeneticVariation GWASCAT Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. 21804548

2011
dbSNP: rs11071559
rs11071559
RORA
CUI: C0004096
Disease: Asthma
Asthma 		C 0.820 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738

2019
dbSNP: rs11071559
rs11071559
RORA
CUI: C0004096
Disease: Asthma
Asthma 		C 0.820 GeneticVariation GWASCAT Identification of a new locus at 16q12 associated with time to asthma onset. 27130862

2016
dbSNP: rs11071559
rs11071559
RORA
CUI: C0004096
Disease: Asthma
Asthma 		C 0.820 GeneticVariation GWASCAT A large-scale, consortium-based genomewide association study of asthma. 20860503

2010
dbSNP: rs11078927
rs11078927
GSDMB
CUI: C0004096
Disease: Asthma
Asthma 		C 0.820 GeneticVariation GWASCAT A meta-analysis of genome-wide association studies of asthma in Puerto Ricans. 28461288

2017
dbSNP: rs11078927
rs11078927
GSDMB
CUI: C0004096
Disease: Asthma
Asthma 		0.820 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549

2011
dbSNP: rs2244012
rs2244012
RAD50
CUI: C0004096
Disease: Asthma
Asthma 		0.820 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965

2016
dbSNP: rs2244012
rs2244012
RAD50
CUI: C0004096
Disease: Asthma
Asthma 		C 0.820 GeneticVariation GWASCAT Multiple SNPs in the RAD50-IL13 region on chromosome 5q31.1 were associated with asthma: rs2244012 in intron 2 of RAD50 (P = 3.04E-07). 20159242

2010
dbSNP: rs2290400
rs2290400
GSDMB
CUI: C0004096
Disease: Asthma
Asthma 		C 0.820 GeneticVariation GWASCAT Combining genomewide association study and lung eQTL analysis provides evidence for novel genes associated with asthma. 27439200

2016
dbSNP: rs3771180
rs3771180
IL18R1 ; IL1RL1
CUI: C0004096
Disease: Asthma
Asthma 		T 0.820 GeneticVariation GWASCAT Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. 29273806

2018
dbSNP: rs3771180
rs3771180
IL18R1 ; IL1RL1
CUI: C0004096
Disease: Asthma
Asthma 		0.820 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. 21804549

2011
dbSNP: rs3859192
rs3859192
GSDMA
CUI: C0004096
Disease: Asthma
Asthma 		T 0.820 GeneticVariation GWASCAT Identification of a new locus at 16q12 associated with time to asthma onset. 27130862

2016
dbSNP: rs4129267
rs4129267
IL6R
CUI: C0004096
Disease: Asthma
Asthma 		C 0.820 GeneticVariation GWASCAT Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. 29273806

2018