Source: GWASCAT

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2274223
rs2274223
PLCE1
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		G 0.900 GeneticVariation GWASCAT Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations. 21642993

2011
dbSNP: rs671
rs671
ALDH2
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		A 0.880 GeneticVariation GWASCAT Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk. 19698717

2009
dbSNP: rs1229984
rs1229984
ADH1B
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		G 0.840 GeneticVariation GWASCAT Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk. 19698717

2009
dbSNP: rs3765524
rs3765524
PLCE1
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		T 0.820 GeneticVariation GWASCAT A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma. 20729852

2010
dbSNP: rs738722
rs738722
CHEK2
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		T 0.810 GeneticVariation GWASCAT A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma. 20729852

2010
dbSNP: rs1042026
rs1042026
ADH1B
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		0.800 GeneticVariation GWASCAT Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs11066280
rs11066280
HECTD4
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		A 0.800 GeneticVariation GWASCAT Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations. 21642993

2011
dbSNP: rs17450420
rs17450420
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		0.800 GeneticVariation GWASCAT Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs17761864
rs17761864
SMG6
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		A 0.800 GeneticVariation GWASCAT Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs2074356
rs2074356
HECTD4
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		T 0.800 GeneticVariation GWASCAT Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations. 21642993

2011
dbSNP: rs2239612
rs2239612
ST6GAL1
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		T 0.800 GeneticVariation GWASCAT Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs2239815
rs2239815
XBP1
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		T 0.800 GeneticVariation GWASCAT Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs2847281
rs2847281
PTPN2
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		C 0.800 GeneticVariation GWASCAT Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs3805322
rs3805322
ADH4 ; LOC100507053
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		0.800 GeneticVariation GWASCAT Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs4785204
rs4785204
HEATR3
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		T 0.800 GeneticVariation GWASCAT Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs4822983
rs4822983
CHEK2
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		T 0.800 GeneticVariation GWASCAT Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs6503659
rs6503659
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		A 0.800 GeneticVariation GWASCAT Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs9288520
rs9288520
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		0.800 GeneticVariation GWASCAT Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. 22960999

2012
dbSNP: rs10052657
rs10052657
PDE4D
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		C 0.700 GeneticVariation GWASCAT Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations. 21642993

2011
dbSNP: rs10058728
rs10058728
CSNK1A1
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		T 0.700 GeneticVariation GWASCAT Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations. 21642993

2011
dbSNP: rs10484761
rs10484761
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		G 0.700 GeneticVariation GWASCAT Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations. 21642993

2011
dbSNP: rs1050631
rs1050631
SLC39A6
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		T 0.700 GeneticVariation GWASCAT Genome-wide association study identifies common variants in SLC39A6 associated with length of survival in esophageal squamous-cell carcinoma. 23644492

2013
dbSNP: rs11066015
rs11066015
ACAD10
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		A 0.700 GeneticVariation GWASCAT Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations. 21642993

2011
dbSNP: rs2014300
rs2014300
RUNX1
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		G 0.700 GeneticVariation GWASCAT Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations. 21642993

2011
dbSNP: rs6772209
rs6772209
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		G 0.700 GeneticVariation GWASCAT Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations. 21642993

2011