DisGeNET - a database of gene-disease associations

Source: GWASCAT

Disease: White Blood Cell Count procedure ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs11264422

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Genetic analyses of diverse populations improves discovery for complex traits.

31217584

2019

dbSNP:

rs12075

ACKR1 ; CADM3-AS1

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Genetic analyses of diverse populations improves discovery for complex traits.

31217584

2019

dbSNP:

rs12075

ACKR1 ; CADM3-AS1

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network.

22037903

2012

dbSNP:

rs1371799

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT).

21738479

2011

dbSNP:

rs16993221

RUNX1 ; LOC100506403

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Genetic associations with C-reactive protein level and white blood cell count in the KARE study.

22788528

2013

dbSNP:

rs17609240

GSDMA

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.

19820697

2009

dbSNP:

rs1962508

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Genetic analyses of diverse populations improves discovery for complex traits.

31217584

2019

dbSNP:

rs2227139

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.

19820697

2009

dbSNP:

rs2340727

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Genetic analyses of diverse populations improves discovery for complex traits.

31217584

2019

dbSNP:

rs2340727

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children.

23263863

2013

dbSNP:

rs2517510

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Multiple loci are associated with white blood cell phenotypes.

21738480

2011

dbSNP:

rs2518564

AIM2

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Genetic analyses of diverse populations improves discovery for complex traits.

31217584

2019

dbSNP:

rs2518564

AIM2

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Trans-ethnic meta-analysis of white blood cell phenotypes.

25096241

2014

dbSNP:

rs2524079

HLA-B

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Genetic analyses of diverse populations improves discovery for complex traits.

31217584

2019

dbSNP:

rs2524079

HLA-B

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Genome-wide association of white blood cell counts in Hispanic/Latino Americans: the Hispanic Community Health Study/Study of Latinos.

28158719

2017

dbSNP:

rs2524079

HLA-B

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

27863252

2016

dbSNP:

rs2814778

ACKR1 ; CADM3-AS1

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa.

31675503

2019

dbSNP:

rs2814778

ACKR1 ; CADM3-AS1

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Genetic analyses of diverse populations improves discovery for complex traits.

31217584

2019

dbSNP:

rs2814778

ACKR1 ; CADM3-AS1

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Analyses of genome wide association data, cytokines, and gene expression in African-Americans with benign ethnic neutropenia.

29596498

2018

dbSNP:

rs2814778

ACKR1 ; CADM3-AS1

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Genome-wide association of white blood cell counts in Hispanic/Latino Americans: the Hispanic Community Health Study/Study of Latinos.

28158719

2017

dbSNP:

rs2814778

ACKR1 ; CADM3-AS1

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

These results validate the previously reported association between WBC and of the regulatory variant rs2814778 in the promoter region, which causes the Duffy negative phenotype (Fy-/-).

22037903

2012

dbSNP:

rs385893

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs3859192

GSDMA

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Genetic analyses of diverse populations improves discovery for complex traits.

31217584

2019

dbSNP:

rs3859192

GSDMA

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network.

22037903

2012

dbSNP:

rs445

CDK6

CUI:	C0023508
Disease:	White Blood Cell Count procedure

White Blood Cell Count procedure

0.800

GeneticVariation

GWASCAT

Genetic analyses of diverse populations improves discovery for complex traits.

31217584

2019