Source: GWASCAT

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1051730
rs1051730
CHRNA3
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		A 0.900 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245

2015
dbSNP: rs8034191
rs8034191
HYKK
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		T 0.880 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245

2015
dbSNP: rs8034191
rs8034191
HYKK
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		C 0.880 GeneticVariation GWASCAT The C allele of the rs8034191 SNP was estimated to have a population attributable risk for COPD of 12.2%. 19300482

2009
dbSNP: rs13180
rs13180
IREB2
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.850 GeneticVariation GWASCAT Variants in FAM13A are associated with chronic obstructive pulmonary disease. 20173748

2010
dbSNP: rs7671167
rs7671167
FAM13A
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.840 GeneticVariation GWASCAT Variants in FAM13A are associated with chronic obstructive pulmonary disease. 20173748

2010
dbSNP: rs13118928
rs13118928
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.830 GeneticVariation GWASCAT Variants in FAM13A are associated with chronic obstructive pulmonary disease. 20173748

2010
dbSNP: rs7937
rs7937
RAB4B ; MIA-RAB4B ; RAB4B-EGLN2
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		T 0.830 GeneticVariation GWASCAT Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. 28166215

2017
dbSNP: rs7937
rs7937
RAB4B ; MIA-RAB4B ; RAB4B-EGLN2
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.830 GeneticVariation GWASCAT Genotyping this single nucleotide polymorphism (SNP) and another nearby SNP in linkage disequilibrium (rs2604894) in 2859 subjects from the family-based International COPD Genetics Network study (ICGN) demonstrated supportive evidence for association for COPD (P = 0.28 and 0.11 for rs7937 and rs2604894), pre-bronchodilator FEV(1) (P = 0.08 and 0.04) and severe (GOLD 3&4) COPD (P = 0.09 and 0.017). 22080838

2012
dbSNP: rs1828591
rs1828591
LOC105377462
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.820 GeneticVariation GWASCAT A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci. 19300482

2009
dbSNP: rs2869967
rs2869967
FAM13A ; LOC105377327
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		C 0.820 GeneticVariation GWASCAT Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease. 25241909

2014
dbSNP: rs12914385
rs12914385
CHRNA3
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.810 GeneticVariation GWASCAT The genetics of smoking in individuals with chronic obstructive pulmonary disease. 29631575

2018
dbSNP: rs12914385
rs12914385
CHRNA3
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		T 0.810 GeneticVariation GWASCAT IREB2 and GALC are associated with pulmonary artery enlargement in chronic obstructive pulmonary disease. 25101718

2015
dbSNP: rs12914385
rs12914385
CHRNA3
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		T 0.810 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245

2015
dbSNP: rs12914385
rs12914385
CHRNA3
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.810 GeneticVariation GWASCAT Genetic susceptibility for chronic bronchitis in chronic obstructive pulmonary disease. 25241909

2014
dbSNP: rs12914385
rs12914385
CHRNA3
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		T 0.810 GeneticVariation GWASCAT Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis. 24621683

2014
dbSNP: rs9296092
rs9296092
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		G 0.810 GeneticVariation GWASCAT Genome-wide association study of smoking behaviours in patients with COPD. 21685187

2011
dbSNP: rs10928927
rs10928927
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		T 0.800 GeneticVariation GWASCAT Genome-wide association study of smoking behaviours in patients with COPD. 21685187

2011
dbSNP: rs114216682
rs114216682
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		G 0.800 GeneticVariation GWASCAT Genome-wide association study of smoking behaviours in patients with COPD. 21685187

2011
dbSNP: rs117607728
rs117607728
PLCE1
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		T 0.800 GeneticVariation GWASCAT Genome-wide association study of smoking behaviours in patients with COPD. 21685187

2011
dbSNP: rs11858836
rs11858836
IREB2
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		A 0.800 GeneticVariation GWASCAT Common and Rare Variants Genetic Association Analysis of Cigarettes per Day Among Ever-Smokers in Chronic Obstructive Pulmonary Disease Cases and Controls. 29767774

2019
dbSNP: rs11858836
rs11858836
IREB2
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.800 GeneticVariation GWASCAT A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. 22080838

2012
dbSNP: rs13141641
rs13141641
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		T 0.800 GeneticVariation GWASCAT Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. 28166215

2017
dbSNP: rs13141641
rs13141641
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		T 0.800 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245

2015
dbSNP: rs13141641
rs13141641
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		T 0.800 GeneticVariation GWASCAT Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis. 24621683

2014
dbSNP: rs13141641
rs13141641
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.800 GeneticVariation GWASCAT A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13. 22080838

2012