Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2430561
rs2430561
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.020 GeneticVariation BEFREE IFN-γ rs2430561 T > A and IL-8 rs4073 A > T genotypes and allele frequencies were not associated with the oral lichen planus group or the normal group. 30290294

2018

dbSNP: rs2430561
rs2430561
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.020 GeneticVariation BEFREE The IFN-γ (+874 in intron 1, rs2430561) TT genotype, which has been reported to be associated with high IFN-γ production, was hypothesized to be associated with susceptibility to OLP in the Thai population. 22041017

2012

dbSNP: rs148704956
rs148704956
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.010 GeneticVariation BEFREE IL17A G197A is associated with a higher susceptibility of developing OLP and these patients seem to present a considerable increase in IL17A serum levels. 28741807

2018

dbSNP: rs16906252
rs16906252
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.010 GeneticVariation BEFREE Genotyping of the C>T allele of rs16906252, predictor of O16-methylguanine-DNA methyltransferase (MGMT) promoter methylation status, in erosive atrophic lesions of oral lichen planus. 31373397

2019

dbSNP: rs1801133
rs1801133
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.010 GeneticVariation BEFREE The current study investigated the association between VDR EcoRV (rs4516035), FokI (rs2228570), ApaI (rs7975232) and TaqI (rs731236), CYP27B1 (rs4646536), CYP24A1 (rs2296241), and MTHFR (rs1801133) gene polymorphisms and risk of oral lichen planus (OLP) occurrence. 26303648

2016

dbSNP: rs189667
rs189667
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.010 GeneticVariation BEFREE Four SNPs of the IL18 gene at positions -137G/C (rs187238), -607C/A (rs1946518), -656G/T (rs1946519), and 1248A/G (rs189667) were analyzed in 151 patients with OLP and 143 normal controls using polymerase chain reaction-sequence-specific primers method, and the serum level of IL-18 protein was determined by enzyme-linked immunosorbent assay (ELISA). 17854431

2007

dbSNP: rs2227306
rs2227306
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.010 GeneticVariation BEFREE Four SNPs of the IL-8 gene at positions -845 T/C (rs2227532), -738 T/A, -251 A/T (rs4073) and +781 C/T (rs2227306) were analyzed in 109 patients with OLP and 101 normal controls using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method. 19842025

2010

dbSNP: rs2228570
rs2228570
VDR
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.010 GeneticVariation BEFREE Our results highlight the possible important role of VDR FokI (rs2228570) and CYP24A1 rs2296241 gene polymorphisms for oral lichen planus susceptibility. 26303648

2016

dbSNP: rs2243143
rs2243143
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.010 GeneticVariation BEFREE Five SNPs of the IL-12A gene at positions rs2243115, rs2243123, rs583911, rs568408, and rs2243143 were performed in 292 patients with OLP and 686 healthy controls from East China. 25258182

2015

dbSNP: rs2296241
rs2296241
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.010 GeneticVariation BEFREE Our results highlight the possible important role of VDR FokI (rs2228570) and CYP24A1 rs2296241 gene polymorphisms for oral lichen planus susceptibility. 26303648

2016

dbSNP: rs2372736
rs2372736
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.010 GeneticVariation BEFREE A whole-genome genotyping scan with linkage analysis was performed using the 10K SNP array to investigate the genetic susceptibility of the Chinese family to OLP, which revealed one maximal nonparametric LOD score of 2.32 (P = 0.0156) for SNP marker rs2372736, defined at the chromosome 3p14-3q13 region encompassing 19 SNPs. 21823092

2011

dbSNP: rs3775291
rs3775291
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.010 GeneticVariation BEFREE No association with OLP risk was observed for the polymorphisms studied in TLR2, TLR4 and CD14 genes or for the rs3775291 polymorphism of the TLR3 gene. 24028589

2013

dbSNP: rs4073
rs4073
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.010 GeneticVariation BEFREE The A-allele of IL-8 rs4073 A > T may have a role in the development and progression of oral lichen planus. 30290294

2018

dbSNP: rs4516035
rs4516035
VDR
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.010 GeneticVariation BEFREE The current study investigated the association between VDR EcoRV (rs4516035), FokI (rs2228570), ApaI (rs7975232) and TaqI (rs731236), CYP27B1 (rs4646536), CYP24A1 (rs2296241), and MTHFR (rs1801133) gene polymorphisms and risk of oral lichen planus (OLP) occurrence. 26303648

2016

dbSNP: rs4646536
rs4646536
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.010 GeneticVariation BEFREE The current study investigated the association between VDR EcoRV (rs4516035), FokI (rs2228570), ApaI (rs7975232) and TaqI (rs731236), CYP27B1 (rs4646536), CYP24A1 (rs2296241), and MTHFR (rs1801133) gene polymorphisms and risk of oral lichen planus (OLP) occurrence. 26303648

2016

dbSNP: rs4774
rs4774
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.010 GeneticVariation BEFREE In conclusion, our data show that the two SNPs rs4774 </span>and rs6498122 are associated with OLP and could also indicate the autoimmune characteristics of OLP. 23489895

2013

dbSNP: rs568408
rs568408
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.010 GeneticVariation BEFREE Our study indicated that the rs568408 variation in IL-12A gene could influence disease susceptibility, and was associated with the severity of OLP in our East Chinese cohort. 25258182

2015

dbSNP: rs5743312
rs5743312
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.010 GeneticVariation BEFREE The findings of the current study suggest that the TT genotype of the rs5743312 TLR3 gene polymorphism may play a significant role in the aetiology of OLP. 24028589

2013

dbSNP: rs6498122
rs6498122
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.010 GeneticVariation BEFREE In conclusion, our data show that the two SNPs rs4774 and rs6498122 are associated with OLP and could also indicate the autoimmune characteristics of OLP. 23489895

2013

dbSNP: rs731236
rs731236
VDR
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.010 GeneticVariation BEFREE The current study investigated the association between VDR EcoRV (rs4516035), FokI (rs2228570), ApaI (rs7975232) and TaqI (rs731236), CYP27B1 (rs4646536), CYP24A1 (rs2296241), and MTHFR (rs1801133) gene polymorphisms and risk of oral lichen planus (OLP) occurrence. 26303648

2016

dbSNP: rs7975232
rs7975232
VDR
CUI: C0206139
Disease: Lichen Planus, Oral
Lichen Planus, Oral
0.010 GeneticVariation BEFREE The current study investigated the association between VDR EcoRV (rs4516035), FokI (rs2228570), ApaI (rs7975232) and TaqI (rs731236), CYP27B1 (rs4646536), CYP24A1 (rs2296241), and MTHFR (rs1801133) gene polymorphisms and risk of oral lichen planus (OLP) occurrence. 26303648

2016